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Displaying results 261 - 270 of 10000 in total
  1. Drug

    Trolamine salicylate

    go.drugbank.com/drugs/DB11079
    Approved

    Trolamine salicylate serves as an active ingredient in topical over-the-counter products for temporary management of mild to moderate muscular and joint pains. … Trolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid.

    Mixtures: Arthritis Extra Strength Roll-ON LotionCategories: Anti-Inflammatory Agents, Non-Steroidal (Non-Selective), Non COX-2 selective NSAIDS
  2. Drug

    Pegfilgrastim

    go.drugbank.com/drugs/DB00019
    ApprovedInvestigational

    [A187601] The drug is approved for use to decrease the incidence of infection, as manifested by febrile neutropenia, in susceptible patients with with non-myeloid cancer receiving myelosuppressive anti-cancer … [L9974] NIOPEG (pegfilgrastim), a biosimilar of NEULASTA®, was approved by Health Canada in April 2024 for the prevention of febrile neutropenia in patients with non-myeloid malignancies receiving myelosuppressive

    Categories: Compounds used in a research, industrial, or household settingProducts: Pelgraz 6 mg solution for injection in a pre-filled syringe, Pelgraz Solution for Injection in pre-filled syringe 6mg/0.6mL
  3. Drug

    Erenumab

    go.drugbank.com/drugs/DB14039
    ApprovedInvestigational

    CGRP receptor, which is believed to play a critical role in migraine [L2823]. … In particular, erenumab-aooe is a human immunoglobulin G2 monoclonal antibody that has high affinity binding to the CGRP receptor [FDA Label].

    Products: AIMOVIG SOLUTION FOR INJECTION IN PRE-FILLED PEN 70MG/ML, AIMOVIG SOLUTION FOR INJECTION IN PRE-FILLED PEN 140MG/ML
  4. Drug

    Metoclopramide

    go.drugbank.com/drugs/DB01233
    ApprovedInvestigational

    It is available in the oral tablet form or in solution, and can also be administered through the intravenous route.[T683] Metoclopramide was initially approved by the FDA in 1980.[A184922] … It can also be used to prevent nausea or vomiting associated with chemotherapy or certain surgical or diagnostic procedures.

    Synonyms: 2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamideCategories: Drugs for Functional Gastrointestinal Disorders, Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  5. Drug

    Vitamin E

    go.drugbank.com/drugs/DB00163
    ApprovedInvestigationalNutraceuticalVet approved

    Though this research is so far inconclusive, vitamin E remains a popular supplement and is generally considered safe by the FDA[FDA Label]. … In 1922, vitamin E was demonstrated to be an essential nutrient[A32448].

    Mixtures: Omega-3 Rx Complete, Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHACategories: Compounds used in a research, industrial, or household setting
  6. Drug

    Nemvaleukin alfa

    go.drugbank.com/drugs/DB18187
    Investigational

    Synonyms: receptor α-chain fragment (139-303), produced in Ch, Fusion protein comprised of a circularly-permuted interleukin-2 (IL-2) with the extracellular domain of IL-2 receptor alpha
  7. Target

    Copper chaperone for superoxide dismutase

    go.drugbank.com/bio_entities/BE0005815
    CarrierTargetHumans

    Delivers copper to copper zinc superoxide dismutase (SOD1)

    Polypeptides: Copper chaperone for superoxide dismutase
  8. Target

    Receptor for retinol uptake STRA6

    go.drugbank.com/bio_entities/BE0009879
    TransporterHumans

    Important for the homeostasis of vitamin A and its derivatives, such as retinoic acid (PubMed:18316031). … STRA6-mediated transport is particularly important in the eye, and under conditions of dietary vitamin A deficiency (Probable). Does not transport retinoic acid (PubMed:18316031)

    Polypeptides: Receptor for retinol uptake STRA6
  9. Drug

    Vigabatrin

    go.drugbank.com/drugs/DB01080
    ApprovedInvestigational

    [A202124] Its use is now generally reserved for patients who have failed alternative therapies, and its US approval by the FDA in 2009 mandated the creation of a drug registry to monitor patients for visual … [L13616] It irreversibly inhibits the enzyme responsible for GABA metabolism, thereby increasing levels of circulating GABA.

    Products: SABRIL 500 MG 50 SASE, Vigabatrin for Oral Solution
  10. Drug

    Aldesleukin

    go.drugbank.com/drugs/DB00041
    ApprovedInvestigational

    This recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon … for this amino acid was deleted during the genetic engineering procedure; c) the molecule has serine substituted for cysteine at amino acid position 125.

    Products: PROLEUKIN POWDER FOR INFUSION 18 miu/vial, Proleukin 18 x 10 6 IE - Pulver zur Herstellung einer Injektions- oder Infusionslösung