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Rurioctocog alfa pegol
go.drugbank.com/drugs/DB16007ApprovedInvestigational[L40119] Rurioctocog alfa pegol is a covalent conjugate of [octocog alfa], which is a recombinant factor VIII produced by recombinant DNA technology from a Chinese hamster ovary cell line. … Bleeding in joints is a common manifestation of hemophilia A, and bleeding episodes can be severe and life-threatening like intracranial hemorrhage.
Synonyms: Antihemophilic factor (recombinant), pegylated (20 kda), Antihemophilic factor (recombinant), pegylated (mw 20000)Oxamniquine
go.drugbank.com/drugs/DB01096Approved(From Martidale, The Extra Pharmacopoeia, 31st ed, p121)
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 InhibitorsRemlarsen
go.drugbank.com/drugs/DB19131InvestigationalRemlarsen is under investigation in clinical trial NCT03601052 (Efficacy, Safety, and Tolerability of Remlarsen (MRG-201) Following Intradermal Injection in Subjects With a History of Keloids).
Synonyms: -cholest-5-en-3-yloxy)hexyl)oxy)-2-hydroxypropyl hydrogen phosphate), complex with rna ((2'-deoxy-2'-fluoro)u-a-g-(2'-deoxy-2'-fluoro)c-a-(2'-deoxy-2'-fluoro)c-(2'-de, Rna, (am-am-cm-a-cm-um-g-um-um-um-a-cm-a-a-a-um-g-g-um-cm-cm-um-a), 3'-(3-((6-((3.beta.)Polythiazide Action Pathway
smpdb.ca/view/SMP0000080Drug actionPolythiazide (also known as Renese or Drenusil) is an organic compound that used for diuretic. It can inhibit the solute carrier family 12 member 3 (also known as sodium-chloride symporter) in the nephron to prevent water reabsorption. S...
Enzymes: Y+L amino acid transporter 2, Y+L amino acid transporter 1Bendroflumethiazide Action Pathway
smpdb.ca/view/SMP0000090Drug actionBendroflumethiazide (also known as bendrofluazide (BAN) or Aprinox) is an organic compound that used for diuretic. It can inhibit the solute carrier family 12 member 3 (also known as sodium-chloride symporter) in the nephron to prevent w...
Enzymes: Y+L amino acid transporter 2, Y+L amino acid transporter 1Quinethazone Action Pathway (old)
smpdb.ca/view/SMP0000091Drug actionQuinethazone, also known under the brand-name Hydromox, is a pharmacologically-active small molecule that belongs to a class of drugs called thiazides. Thiazides and thiazide-like drugs are diuretics commonly employed to control hyperten...
Enzymes: Y+L amino acid transporter 2, Y+L amino acid transporter 1Ethacrynic Acid Action Pathway
smpdb.ca/view/SMP0000097Drug actionEtacrynic acid (also known as ethacrynic acid and Edecrin) is a loop diuretic that can inhibit water reabsorption by binding and inhibiting solute carrier family 12 member 1 (also known as sodium-potassium-chloride cotransporter) in the ...
Enzymes: Y+L amino acid transporter 2, Y+L amino acid transporter 1Hydrochlorothiazide Action Pathway
smpdb.ca/view/SMP0000100Drug actionHydroflumethiazide (also known as Esidrix or Oretic) is an organic compound that used for diuretic. It can inhibit the solute carrier family 12 member 3 (also known as sodium-chloride symporter) in the nephron to prevent water reabsorpti...
Enzymes: Y+L amino acid transporter 2, Y+L amino acid transporter 1Indapamide Action Pathway
smpdb.ca/view/SMP0000110Drug actionIndapamide (also named as Noranat or Veroxil) is a thiazide-like diuretic drug that can be used to treat hypertension and decompensated heart failure. Indapamide can inhibit sodium-chloride symporter in distal convoluted tubule to preven...
Enzymes: Y+L amino acid transporter 2, Y+L amino acid transporter 1Amiloride Action Pathway
smpdb.ca/view/SMP0000133Drug actionAmiloride is a diuretic that inhibits the sodium channels in the late distal convoluted tubule and collecting tube of the nephron where 1-2% of sodium reabsorption occurs. The inhibition of sodium reabsorption results in increased osmola...
Enzymes: Y+L amino acid transporter 2, Y+L amino acid transporter 1