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Fosphenytoin
go.drugbank.com/drugs/DB01320ApprovedInvestigationalIt works by slowing down impulses in the brain that cause seizures.
Choline salicylate
go.drugbank.com/drugs/DB14006ApprovedNutraceuticalCholine Salicylate is the choline salt of salicylic acid, used as an analgesic, antipyretic and antirheumatic. It relieves mild to moderate pain and reduce fever and inflammation or swelling. … The UK government has regulated its use, due to toxicity in those under 16 years of age.
Sinecatechins
go.drugbank.com/drugs/DB01266ApprovedInvestigationalNutraceuticalCatechins constitute 85 to 95% (by weight) of the total drug substance which includes more than 55% of Epigallocatechin gallate (EGCg), other catechin derivatives such as Epicatechin (EC), Epigallocatechin … It is a partially purified fraction of the water extract of green tea leaves from Camellia sinensis, and is a mixture of catechins and other green tea components.
Synonyms: Polyphenon EInsulin degludec
go.drugbank.com/drugs/DB09564ApprovedInvestigational[A18561,A18562,A18563,A18564,A174934] Marketed as the brand name product Tresiba, insulin degludec has a duration of action up to 42 hours allowing for once-daily dosing, typically at bedtime. … [A18561,A18562,A18563,A18564,A174934] Compared to endogenous insulin, insulin degludec has an added hexadecanedioic acid on lysine at the B29 position, allowing for the formation of multi-hexamers.
Quaternium-15
go.drugbank.com/drugs/DB14198ApprovedQuaternium-15 is a quaternary ammonium salt used as a surfactant and preservative in many products including cosmetics. … It is an anti-microbial agent by virtue of being a formaldehyde releaser, however this can also cause contact dermatitis, a symptom of an allergic reaction, especially in those with sensitive skin.
Salmon calcitonin
go.drugbank.com/drugs/DB00017ApprovedInvestigationalSynthetic peptide, 32 residues long formulated as a nasal spray.
Mipomersen
go.drugbank.com/drugs/DB05528ApprovedIt is marketed under the brand name Kynamro in the United States, and the FDA label includes a black box warning of hepatoxicity. … Mipomersen sodium, which was known as the investigational drug, isis-301012, is the salt form of a synthetic phosphorothioate oligonucleotide.
Aluminum zirconium octachlorohydrex gly
go.drugbank.com/drugs/DB11200ApprovedIt is an active antiperspirant agent [L2705], [L2706]. It diffuses into the sweat pores and prevents perspiration (sweat) from leaving the pores. … Interestingly, this chemical has been studied in relation to its possible impact on the microbiome of the human underarms [A32967].
Products: Gillette Hydra Vitamin E, TAG Spin ItInsulin icodec
go.drugbank.com/drugs/DB16693ApprovedInvestigational[L50763] It has also been approved in Japan and Australia. … It is a re-engineered version of the ultra long-acting oral basal insulin OI338, with several modifications introduced to significantly extend the half-life.
Dipyrithione
go.drugbank.com/drugs/DB11327Approved[L2611] It is currently used as a pesticide, and not used in any FDA approved drug products. … [A32825] It may be combined with other ingredients, such as triclosan to serve as antifungal and antibacterial skin treatments.