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Onasemnogene abeparvovec
go.drugbank.com/drugs/DB15528ApprovedInvestigational[L9194] Onasemnogene abeparvovec for therapeutic use and marketing is currently being assessed by the EU and an intrathecal formulation of the drug is currently undergoing clinical development in the USA … [Nusinersen] is another gene therapy that is currently approved by the FDA for the treatment of SMA in pediatric and adult patients.
Categories: Cellular and Gene Therapy, Amino Acids, Peptides, and ProteinsHemoglobin
go.drugbank.com/drugs/DB04945ApprovedInvestigationalWithdrawnIt consists primarily of globin and heme.
Categories: Amino Acids, Peptides, and ProteinsLodoxamide
go.drugbank.com/drugs/DB06794ApprovedAlthough less effective than topical steroids at decreasing inflammation, mast-cell stabilizers offer another treatment option and exhibit minimal adverse effects. … Lodoxamide is marketed under the brand name Alomide by Alcon.
Categories: Decongestants and Antiallergics, Amino Acids, Peptides, and ProteinsAlmasilate
go.drugbank.com/drugs/DB13595ApprovedIt is a crystalline polyhydrate of aluminium/magnesium silicate and mediates its buffering activity by binding hydrogen ions within the polymer. … Almasilate is a buffering antacid that has been used in peptic ulcers and dyspepsia.
Categories: Alimentary Tract and Metabolism, Aluminum and magnesium containing antacidsCefroxadine
go.drugbank.com/drugs/DB11367ApprovedWithdrawnIt was used in Italy but has since been withdrawn. … Cefroxadine is an orally available cephalosporin antibiotic. As part of its drug class, it shares structural properties to [cefalexin] as well as its activity spectrum.
Tubocurarine
go.drugbank.com/drugs/DB01199ApprovedWithdrawn[A216008] Curare is one of the names used to describe plant-derived poisons used by indigenous South Americans to coat the tips of hunting arrows and darts, which were typically derived from plants of … [A216038] Tubocurarine's clinical use was limited by its relatively long duration of action (30-60 minutes)[A216038] and a number of significant side effects.
Pilocarpine
go.drugbank.com/drugs/DB01085ApprovedInvestigational[A262036] Pilocarpine is used to treat dry mouth and various ophthalmic conditions, including elevated intraocular pressure and glaucoma. The usage of glaucoma by pilocarpine dates back to 1875. … A naturally occurring alkaloid derived from the _Pilocarpus_ plants, pilocarpine is a muscarinic acetylcholine agonist.
Categories: Antiglaucoma Preparations and MioticsProducts: PILCARD® 5MG TABLETAS, PILOCARPINA CLORHIDRATO 5MG TABLETAS RECUBIERTAS.Ulipristal
go.drugbank.com/drugs/DB08867ApprovedInvestigationalIt is a derivative of 19-norprogesterone and has both antagonistic and partial agonist activity at the progesterone receptor. … The exact mechanism of action for ulipristal is still currently debated, though there is evidence that it functions by inhibiting ovulation.
Categories: Genito Urinary System and Sex Hormones, Sex Hormones and Modulators of the Genital SystemProducts: Ella Tablet 30mg, ESMYA TABLET 5MG