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Displaying results 2781 - 2790 of 10000 in total
  1. Drug

    Mevastatin

    go.drugbank.com/drugs/DB06693
    Experimental

    Two years later, the research group isolated a compound structurally similar to hydroxymethylglutarate (HMG) that inhibited the incorporation of acetate. … During a search for antibiotic compounds produced by fungi in 1971, Akira Endo at Sankyo Co. (Japan) discovered a class of compounds that appeared to lower plasma cholesterol levels.

  2. Drug

    Zinc acetate

    go.drugbank.com/drugs/DB14487
    ApprovedInvestigational

    Mixtures: Johnson and Johnson First Aid All Purpose 160 CT, Benadryl Bug Bite Relief
  3. Drug

    Iopodic acid

    go.drugbank.com/drugs/DB09333
    ApprovedWithdrawn

    On September 22, 1981, ipodate was submitted again by the company Schering AG but it is currently under an inactive status.[L1082] … [A32080] Due to its particular structure, it presents a high degree of lipid solubility and a radiopaque property. It was developed and filed to the FDA by the company BRACCO.

  4. Drug

    13-deoxydoxorubicin

    go.drugbank.com/drugs/DB05706
    Investigational

    GPX-100 is an anthracycline anticancer drug that belongs to the family of drugs called antitumor antibiotics.

  5. Drug

    Thyroglobulin

    go.drugbank.com/drugs/DB01584
    ApprovedWithdrawn

    Thyroglobulin (also known as Tg) is an enzyme thyroid hormone used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). … The active form of thyroxine, triiodothyronine, is produced both within the thyroid gland and periphery by 5'-deiodinase.

  6. Indication

    Aspiration Pneumonitis

    go.drugbank.com/conditions/DBCOND0075845
    Drugs: Cortisone acetate · Dexamethasone · Hydrocortisone · Methylprednisolone · Prednisolone · Prednisone
    Synonyms: Pneumonitis due to inhalation of food and vomit
  7. Indication

    Toxocariasis

    go.drugbank.com/conditions/DBCOND0009840
    Drugs: Mebendazole
    Synonyms: Infection due to toxocara
  8. Drug

    Zoliflodacin

    go.drugbank.com/drugs/DB12817
    ApprovedInvestigational

    Gonorrhea, caused by Neisseria gonorrhoeae, presents a significant public health challenge due to increasing antimicrobial resistance. … [A275268] Zoliflodacin is a first-in-class spiropyrimidinetrione antibiotic designed to address this need by inhibiting bacterial type II topoisomerases (DNA gyrase and topoisomerase IV), thereby blocking

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates
  9. Drug

    Levorphanol

    go.drugbank.com/drugs/DB00854
    Approved

    It is nearly as effective orally as by injection.

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  10. Indication

    Rocky Mountain Spotted Fever

    go.drugbank.com/conditions/DBCOND0000434
    Drugs: Minocycline · Tetracycline
    Synonyms: Spotted fever due to Rickettsia rickettsii, Spotted fever due to Rickttsia rickettsii