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Displaying results 271 - 280 of 661 in total
  1. Drug

    Baricitinib

    go.drugbank.com/drugs/DB11817
    ApprovedInvestigational

    [A248400] The EC later approved baricitinib for the treatment of atopic dermatitis, making it the first JAK inhibitor used for this indication in Europe. … [L41760] Baricitinib was first approved by the European Commission (EC) in February 2017 for the treatment of rheumatoid arthritis in adults [A248395] and was later approved by the FDA in 2018.

  2. Drug

    Denileukin diftitox

    go.drugbank.com/drugs/DB00004
    ApprovedInvestigational

    Denileukin diftitox is an IL2-receptor-directed cytotoxin, is a recombinant DNA-derived fusion protein composed of the amino acid sequences for diphtheria toxin fragments A and B (Met1-Thr387)-His and the sequence for human interleukin-2...

  3. Drug

    Flubendazole

    go.drugbank.com/drugs/DB08974
    ApprovedInvestigationalWithdrawn

    It is available OTC in Europe.

  4. Drug

    Daridorexant

    go.drugbank.com/drugs/DB15031
    ApprovedInvestigational

    [A244280] Daridorexant was approved by the European Commission on May 3, 2022, as the first dual orexin receptor antagonist approved in the market,[L41725] and by Health Canada on April 26, 2023.

  5. Indication

    Mucocutaneous Leishmaniasis

    go.drugbank.com/conditions/DBCOND0051127
    Drugs: Amphotericin B · Miltefosine · Sodium stibogluconate
    Synonyms: Leishmania braziliensis complex
  6. Drug

    Sultopride

    go.drugbank.com/drugs/DB13273
    Approved

    Sultopride is used in Japan, Hong Kong, and Europe to treat schizophrenia. It is of the drug class atypical antipsychotics [L5626].

  7. Indication

    Wilson's Disease

    go.drugbank.com/conditions/DBCOND0032702
    Drugs: Penicillamine · Triethylenetetramine · Zinc
    Synonyms: Copper storage disease, Iron &/or copper &/or magnesium disorder (& [haemochromatosis] or [Wilson's disease])
  8. Drug

    Brinzolamide

    go.drugbank.com/drugs/DB01194
    Approved

    [L35310,L35315] In Europe, it was also approved as a combination product with timolol in 2008.[L35320]

  9. Drug

    Benmoxin

    go.drugbank.com/drugs/DB09246
    ApprovedWithdrawn

    It was first synthesized in 1967 and rapidly used in Europe as an antidepressant. However, this agent is no longer marketed.

  10. Drug

    Cinacalcet

    go.drugbank.com/drugs/DB01012
    ApprovedInvestigational

    Cinacalcet is a calcimimetic sold by Amgen under the trade name Sensipar® in North America and Australia and as Mimpara® in Europe.