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Nylidrin
go.drugbank.com/drugs/DB06152ApprovedWithdrawnNylidrin, also known as _buphenine_ belongs to the category of drugs called _vasodilators_, which relax blood vessels and increase blood flow. Nylidrin is a peripheral vasodilator. … Nylidrin is utilized to treat several disorders that may benefit from increased blood flow (for example, certain mental disorders, blood vessel disease due to diabetes, frostbite, night leg cramps, and
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: PMS-nylidrin Tab 6mgSplicing factor 3B subunit 1
go.drugbank.com/bio_entities/BE0009359TargetHumansComponent of the 17S U2 SnRNP complex of the spliceosome, a large ribonucleoprotein complex that removes introns from transcribed pre-mRNAs (PubMed:12234937, PubMed:27720643, PubMed:32494006, PubMed:34822310, PubMed:36104565). The 17S U2...
Synonyms: SAP 155, Spliceosome-associated protein 155Phosphatidylethanolamine Biosynthesis PE(15:0/18:3(9Z,12Z,15Z))
smpdb.ca/view/SMP0015124MetabolicPhosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone. They are the second most abundant phospholipid in eukaryotic cell membranes, and contrary to phospha...
Drugs: Choline · Serine · Phosphatidyl serine · ATP · Cytidine-5'-Triphosphate · Ethanolamine +1 moreDaraxonrasib
go.drugbank.com/drugs/DB22308ApprovedInvestigational[L64039,L64041] Because it targets a broad range of RAS genotypes, it treats tumors with or without an identified RAS mutation and does not require a companion diagnostic test. … RAS variants rather than a single mutation.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesMN-246
go.drugbank.com/drugs/DB05981ExperimentalMN-246 is a novel ß3-adrenergic receptor agonist developed for the treatment of urinary incontinence by MediciNova Inc.
Camizestrant
go.drugbank.com/drugs/DB19218ApprovedInvestigational[L64094,L64107] In pre- or peri-menopausal women and in men, camizestrant plus a CDK4/6 inhibitor is combined with an LHRH agonist or antagonist. … Camizestrant is an oral selective estrogen receptor degrader (SERD) and estrogen receptor (ER) antagonist used in combination with a CDK4/6 inhibitor to treat hormone receptor-positive, HER2-negative locally
Categories: Cytochrome P-450 CYP1A2 Inducers, Cytochrome P-450 SubstratesFostemsavir
go.drugbank.com/drugs/DB11796ApprovedInvestigational[L14867] The discovery of gp120 as a potential target of interest in the treatment of HIV-1 infection is relatively recent, and was born out of a desire to find alternative target proteins (i.e. mechanistically … Fostemsavir is the phosphonooxymethyl prodrug of temsavir, a novel HIV-1 attachment inhibitor.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesGantenerumab
go.drugbank.com/drugs/DB12034Investigationalto reduce Aβ aggregation and remove Aβ plaques. … Gantenerumab binds to a unique Aβ epitope compared to other anti-Aβ antibodies and preferentially recognizes Aβ oligomers and fibrils over monomers.[A244720]
Cinchocaine
go.drugbank.com/drugs/DB00527ApprovedVet approvedA local anesthetic of the amide type now generally used for surface anesthesia.
Mixtures: ULTRAPROCT %0,09+%0,09+%0,5 MERHEM, 10 G, Dibucaine HCl 0.5% / Lidocaine 15% / Phenylephrine HCl 1% / Prilocaine 5%De Novo Triacylglycerol Biosynthesis TG(15:0/18:3(9Z,12Z,15Z)/18:3(9Z,12Z,15Z))
smpdb.ca/view/SMP0017478MetabolicA triglyceride (TG, triacylglycerol, TAG, or triacylglyceride) is an ester derived from glycerol and three fatty acids. Triglycerides are the main constituents of body fat in humans and other animals, as well as vegetable fat. They are a...