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Displaying results 2831 - 2840 of 10000 in total
  1. Drug

    Eflapegrastim

    go.drugbank.com/drugs/DB15001
    ApprovedInvestigational

    [L43135] In September 2022, eflapegrastim was approved by the US FDA as a prophylactic against infection, as manifested by febrile neutropenia, in patients receiving certain myelosuppressive anti-cancer … in which the patient develops an infection during a period of significant neutropenia.

    Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating Agents
  2. Drug

    Dasiglucagon

    go.drugbank.com/drugs/DB15226
    Approved

    It is characterized by neurological impairment, with manifestations like loss of consciousness and seizure. … [L39190] Severe hypoglycemia is an acute, life-threatening medical condition resulting from a profound drop in blood glucose levels.

    Categories: Sex Hormones and Insulins, Amino Acids, Peptides, and Proteins
  3. Target

    Serine/threonine-protein kinase Nek5

    go.drugbank.com/bio_entities/BE0009499
    TargetHumans

    Synonyms: Never in mitosis A-related kinase 5
  4. Target

    Chloride anion exchanger

    go.drugbank.com/bio_entities/BE0010211
    TransporterHumans

    Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation (By similarity) … Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia (PubMed:16606687, PubMed:19321737, PubMed:22159084, PubMed:22627094).

    Synonyms: Down-regulated in adenoma
  5. Target

    Serine/threonine-protein kinase Nek7

    go.drugbank.com/bio_entities/BE0017593
    TargetHumans

    Protein kinase which plays an important role in mitotic cell cycle progression (PubMed:17101132, PubMed:19941817, PubMed:31409757). … Acts by unlocking NLRP3 following NLRP3 tranlocation into the microtubule organizing center (MTOC), relieving NLRP3 autoinhibition and promoting formation of the NLRP3:PYCARD complex, and activation of

    Synonyms: Never in mitosis A-related kinase 7
  6. Drug

    Calaspargase pegol

    go.drugbank.com/drugs/DB14730
    ApprovedInvestigational

    Asparaginase is an important agent used to treat acute lymphoblastic leukemia (ALL) [A40270]. … Asparagine is incorporated into most proteins, and the synthesis of proteins is stopped when asparagine is absent, which inhibits RNA and DNA synthesis, resulting in a halt in cellular proliferation.

    Categories: Compounds used in a research, industrial, or household setting, Enzymes and Coenzymes
  7. Indication

    Chlamydial ophthalmia neonatorum

    go.drugbank.com/conditions/DBCOND0020671
    Drugs: Erythromycin
    Synonyms: Neonatal conjunctivitis and dacryocystitis
  8. Indication

    Proctitis

    go.drugbank.com/conditions/DBCOND0011080
    Drugs: Aluminum subacetate · Balsam of Peru · Calcium carbonate · Esculin · Fluocortolone caproate · Fluocortolone pivalate +7 more
    Synonyms: Other specified diseases of anus and rectum
  9. Drug

    Brilliant blue G

    go.drugbank.com/drugs/DB15594
    Approved

    Brilliant Blue G is used in an ophthalmic solution for staining the internal limiting membrane (ILM) of the eye during ophthalmic procedures. … It was approved by the FDA for ophthalmic use on December 20, 2019.[L10830]

    Categories: Indicators and Reagents, Compounds used in a research, industrial, or household setting
  10. Drug

    Arbutamine

    go.drugbank.com/drugs/DB01102
    Approved

    Arbutamine, administered through a closed-loop, computer-controlled drug-delivery system, is indicated to elicit acute cardiovascular responses, similar to those produced by exercise, in order to aid in … diagnosing the presence or absence of coronary artery disease in patients who cannot exercise adequately .

    Categories: Adrenergic and Dopaminergic Agents, Compounds used in a research, industrial, or household setting