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Displaying results 2881 - 2890 of 10000 in total
  1. Drug

    Bertilimumab

    go.drugbank.com/drugs/DB05429
    Investigational

    Bertilimumab is a fully human anti-eotaxin monoclonal antibody with potential in the treatment of allergic disorders, has moved into pre-clinical development.

    Synonyms: IMMUNOGLOBULIN G4, ANTI-(HUMAN EOTAXIN 1) (HUMAN MONOCLONAL CAT-213 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL CAT-213 .KAPPA.-CHAIN, DIMER
  2. Pathway

    Alprenolol Action Pathway

    smpdb.ca/view/SMP0000297
    Drug action

    Alprenolol (also known as alfeprol, alpheprol or alprenololum) a beta blocker (non-selective) that block beta-1 adrenergic receptor in heart. Blocking beta-1 adrenergic receptor could prevent the binding of epinephrine and norepinephrine...

    Drugs: ATP · Alprenolol · Potassium cation · Calcium
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  3. Pathway

    Betaxolol Action Pathway

    smpdb.ca/view/SMP0000299
    Drug action

    Betaxolol (also known as Betoptic or Lokren) is a selective beta blocker that can block beta1-adrenergic receptors and beta2-adrenergic receptors. Blocking of beta1-adrenergic receptors in heart and vascular smooth muscle can lead to red...

    Drugs: ATP · Betaxolol · Potassium cation · Calcium
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  4. Pathway

    Esmolol Action Pathway

    smpdb.ca/view/SMP0000301
    Drug action

    Esmolol, sold as Brevibloc, is a cardioselective beta-1 receptor blocker drug. As a beta-blocker, esmolol blocks the agonistic effect of the sympathetic neurotransmitters by competing for receptor binding sites, and as it is cardioselect...

    Drugs: ATP · Esmolol · Potassium cation · Calcium
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  5. Pathway

    Nadolol Action Pathway

    smpdb.ca/view/SMP0000303
    Drug action

    Nadolol (also known as Corgard or Solgol) is a beta blocker (non-selective) that are used for treat high blood pressure or chest pain. Nadolol bind to beta1-adrenergic receptors in heart and vascular smooth muscle to block the binding of...

    Drugs: ATP · Nadolol · Potassium cation · Calcium
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  6. Pathway

    Oxprenolol Action Pathway

    smpdb.ca/view/SMP0000304
    Drug action

    Oxprenolol (also known as Trasacor or Trasicor) is a beta blocker (non-selective) that are used for treat high blood pressure or chest pain. Oxprenolol bind to beta1-adrenergic receptors in heart and vascular smooth muscle to block the b...

    Drugs: ATP · Potassium cation · Calcium · Oxprenolol
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  7. Pathway

    Propranolol Action Pathway

    smpdb.ca/view/SMP0000307
    Drug action

    Propranolol, a non-cardioselective beta blocker, inhibits sympathetic stimulation by competing with neurotransmitters like catecholamines to bind beta(1)-adrenergic receptors of the heart and vascular smooth muscle. Propranolol binding r...

    Drugs: ATP · Propranolol · Potassium cation · Calcium
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  8. Pathway

    Quinidine Action Pathway

    smpdb.ca/view/SMP0000323
    Drug action

    This pathway illustrates the quinidine targets involved in antiarrhythmic therapy. Contractile activity of cardiac myocytes is elicited via action potentials mediated by a number of ion channel proteins. During rest, or diastole, cells m...

    Drugs: ATP · Quinidine · Potassium cation · Calcium
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  9. Pathway

    Disopyramide Action Pathway

    smpdb.ca/view/SMP0000325
    Drug action

    This pathway illustrates the disopyramide targets involved in antiarrhythmic therapy. Contractile activity of cardiac myocytes is elicited via action potentials mediated by a number of ion channel proteins. During rest, or diastole, cell...

    Drugs: ATP · Disopyramide · Potassium cation · Calcium
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2
  10. Pathway

    Nebivolol Action Pathway

    smpdb.ca/view/SMP0000366
    Drug action

    Nebivolol (also known as Bystolic or Nebivololum) is a β1-receptor blocker (selective β1-receptor antagonist) that can bind and inhibit Beta-1 adrenergic receptor in muscule and heart. Nebivolol competes with epinephrine or other beta-...

    Drugs: ATP · Potassium cation · Calcium · Nebivolol
    Enzymes: Potassium voltage-gated channel subfamily E member 1, Potassium voltage-gated channel subfamily E member 2