Search
Larotrectinib
go.drugbank.com/drugs/DB14723ApprovedInvestigationalOn April 10, 2025, the FDA granted full drug approval.[L52805] … Larotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays
Categories: Heterocyclic Compounds, 1-Ring, Antineoplastic and Immunomodulating AgentsProducts: VITRAKVI 100 MG SERT KAPSÜL, 56 ADET, VITRAKVI 20 MG/ML ORAL ÇÖZELTİ, 2x50 MLHydroxyurea
go.drugbank.com/drugs/DB01005ApprovedInvestigationalneed for therapeutic monitoring, and serious side effects of secondary cancer and birth defects. … Hydroxyurea is a non-alkylating antineoplastic agent that was first synthesized in 1869 but was not characterized biologically until 1928.
Categories: Antineoplastic and Immunomodulating Agents, Cytochrome P-450 CYP2D6 InhibitorsSynonyms: N-Hydroxyurea, N-CarbamoylhydroxylamineMagnesium oxide
go.drugbank.com/drugs/DB01377ApprovedInvestigationalIt is used as an antacid and mild laxative and has many nonmedicinal uses.
Mixtures: PICOPREP 10 MG / 3,5 G /12 G ORAL ÇÖZELTI IÇIN TOZ, 2 SAŞE, DIMAG 365 MG TEK KULLANIMLIK TOZ ICEREN SAŞE, 10 ADETCategories: Alimentary Tract and Metabolism, Aluminum and magnesium containing antacidsKB3305
go.drugbank.com/drugs/DB06349ExperimentalKB3305 is an investigational liver selective antagonist for the glucocorticoid receptor, developed by Karo Bio for the treatment of Type 2 Diabetes.
Categories: 17-Ketosteroids, Bile Acids and SaltsSynonyms: 3.BETA.,5.BETA.,7.ALPHA.,12.ALPHA.)-7,12-DIHYDROXY-3-(2-((4-((11.BETA.,17.BETA.)-17-HYDROXY-3-OXO-17-(1-PROPYN-1-YL)ESTRA-4,9-DIEN-11-YL)PHENYL)METHYLAMINO)ETHOXY)CHOLAN-24-OIC ACID, CHOLAN-24-OIC ACID, 7,12-DIHYDROXY-3-(2-((4-((11.BETA.,17.BETA.)-17-HYDROXY-3-OXO-17-(1-PROPYN-1-YL)ESTRA-4,9-DIEN-11-YL)PHENYL)METHYLAMINO)ETHOXY)-, (3.BETA.,5.BETA.,7.ALPHA.,12.ALPHA.)-Pimecrolimus
go.drugbank.com/drugs/DB00337ApprovedInvestigationalIt is currently available as a topic cream used in the treatment of atopic dermatitis (eczema).
Categories: Skin and Mucous Membrane Agents, Cytochrome P-450 SubstratesProducts: Elidel 10 mg/g Creme, ELIDEL %1 KREM, 15 GDexibuprofen
go.drugbank.com/drugs/DB09213ApprovedWithdrawnDexibuprofen has a slower dissolution rate in the simulated gastric and enteric juices compared with the racemic ibuprofen and displays improved oral bioavilability [A19259]. … It is proposed to be more pharmacologically active and tolerable with a better safety profile than ibuprofen due to higher concentration of active S enantiomer.
Mixtures: TAFLAX® GRIP, TAFLAX®FORTE TABLETAS RECUBIERTASCategories: Ibuprofen and isomer, Antiinflammatory and Antirheumatic ProductsOxygen
go.drugbank.com/drugs/DB09140ApprovedInvestigationalVet approvedOxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. … Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow resistance in the diseased lung, leading to decreased cardiovascular workload in
Mixtures: Carbon Dioxide 1% W Oxygen, Donopa 50%/50% v/v Gas zur medizinischen Anwendung, druckverdichtetProducts: Oxygen Size M, Oxygen Compressed UN 1072 Refrigerated UN 1073Indocyanine green acid form
go.drugbank.com/drugs/DB09374ApprovedInvestigationalEach vial of Indocyanine Green for Injection USP contains 25 mg of Indocyanine Green as a sterile lyophilized powder with no more than 5% sodium iodide. … The chemical name for Indocyanine Green is 1 H-Benz[e]indolium, 2-[7-[1,3-dihydro-1,1-dimethyl-3-(4-sulfobutyl)-2H-benz[e] indol-2-ylidene]-1,3,5-heptatrienyl]-1,1-dimethyl-3-(4-sulfobutyl)-,hydroxide,
Categories: Heterocyclic Compounds, 2-Ring, Compounds used in a research, industrial, or household settingProducts: VERDYE 5 mg/ml Injektionszubereitung, ไดแอกโนกรีน(R) ชนิดฉีด 25 มิลลิกรัมLorazepam
go.drugbank.com/drugs/DB00186ApprovedInvestigationalLorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic. … [A957] It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977.
Categories: Hypnotics and Sedatives, Benzodiazepine hypnotics and sedativesSynonyms: o-Chloroxazepam, o-ChlorooxazepamTeriflunomide
go.drugbank.com/drugs/DB08880ApprovedInvestigationalIt is marketed under the name Aubagio® and is indicated for the treatment of multiple sclerosis, specifically relapsing forms. … Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis.
Categories: Leflunomide and metabolite, Antineoplastic and Immunomodulating AgentsSynonyms: (Z)-2-cyano-alpha,alpha,alpha-trifluoro-3-hydroxy-p-crotonotoluidide