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Displaying results 21 - 30 of 125 in total
  1. Target

    Alpha-methylacyl-CoA racemase

    go.drugbank.com/bio_entities/BE0009569
    EnzymeHumans

    Polypeptides: Alpha-methylacyl-CoA racemaseSynonyms: 2-methylacyl-CoA racemase
  2. Target

    Acetyl-CoA carboxylase 1

    go.drugbank.com/bio_entities/BE0000626
    TargetHumans

    Cytosolic enzyme that catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis (PubMed:20457939, PubMed:20952656, PubMed:29899443). … reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA

    Polypeptides: Acetyl-CoA carboxylase 1Function: acetyl-CoA carboxylase activity
  3. Target

    Methylmalonyl-CoA mutase, mitochondrial

    go.drugbank.com/bio_entities/BE0000777
    TargetHumans

    (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle … Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA

    Polypeptides: Methylmalonyl-CoA mutase, mitochondrialSynonyms: Methylmalonyl-CoA isomerase
  4. Target

    Formyl-CoA:oxalate CoA-transferase

    go.drugbank.com/bio_entities/BE0001310
    TargetOxalobacter formigenes

    Catalyzes the transfer of the CoA moiety from formyl-CoA to oxalate (PubMed:15213226, PubMed:18162462, PubMed:18245280, PubMed:2361939, PubMed:9150242).

    Polypeptides: Formyl-CoA:oxalate CoA-transferaseFunction: formyl-CoA transferase activity
  5. Target

    Acetyl-CoA acetyltransferase, cytosolic

    go.drugbank.com/bio_entities/BE0001317
    TargetHumans

    Involved in the biosynthetic pathway of cholesterol

    Polypeptides: Acetyl-CoA acetyltransferase, cytosolicSynonyms: Acetyl-CoA transferase-like protein, Cytosolic acetoacetyl-CoA thiolase
  6. Target

    L-carnitine CoA-transferase

    go.drugbank.com/bio_entities/BE0001666
    TargetEscherichia coli (strain K12)

    Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L-carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. … Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine.

    Polypeptides: L-carnitine CoA-transferaseSynonyms: Crotonobetainyl-CoA:carnitine CoA-transferase
  7. Target

    Glutaryl-CoA dehydrogenase, mitochondrial

    go.drugbank.com/bio_entities/BE0001921
    TargetHumans

    Catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism.

    Polypeptides: Glutaryl-CoA dehydrogenase, mitochondrialFunction: fatty-acyl-CoA binding
  8. Target

    Acyl-CoA thioesterase 2

    go.drugbank.com/bio_entities/BE0002038
    TargetEscherichia coli (strain K12)

    Thioesterase that has relatively broad substrate specificity, hydrolyzing primarily medium- and long-chain acyl-CoA substrates to free fatty acids and CoA (PubMed:1645722, PubMed:20547355, PubMed:24271180 … pathway, and 3,5-dodecadienoyl-CoA, the end product of CLA beta-oxidation, respectively (PubMed:14707139, PubMed:18702504).

    Polypeptides: Acyl-CoA thioesterase 2Synonyms: Acyl-CoA thioesterase II
  9. Target

    4-hydroxybenzoyl-CoA thioesterase

    go.drugbank.com/bio_entities/BE0002496
    TargetPseudomonas sp. (strain CBS-3)

    Hydrolyzes 4-hydroxybenzoate-CoA, and to a lesser extent benzoyl-CoA and 4-chlorobenzoate-CoA. Not active against aliphatic acyl-CoA thioesters, including palmitoyl-CoA, hexanoyl-CoA and acetyl-CoA.

    Polypeptides: 4-hydroxybenzoyl-CoA thioesteraseFunction: 4-hydroxybenzoyl-CoA thioesterase activity
  10. Target

    4-hydroxybenzoyl-CoA thioesterase

    go.drugbank.com/bio_entities/BE0002575
    TargetArthrobacter sp.

    Polypeptides: 4-hydroxybenzoyl-CoA thioesteraseSynonyms: 4-HBA-CoA thioesterase