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Levomilnacipran SNRI - Serotonin Reuptake Inhibition Action Pathway
smpdb.ca/view/SMP0126386Drug actionLevomilnacipran (the more active 1S, 2R - enantiomer of milnacipran) is a serotonin and norepinephrine reuptake inhibitor (SNRI). It is used in the management of major depressive disorder, generalized anxiety disorder, chronic musculoske...
Enzymes: Sodium-dependent serotonin transporterMilnacipran SNRI - Serotonin reuptake Inhibition Action Pathway
smpdb.ca/view/SMP0126399Drug actionMilnacipran is a serotonin and norepinephrine reuptake inhibitor (SNRI). It is used in the management of fibromyalgia, major depressive disorder, generalized anxiety disorder, chronic musculoskeletal pain and diabetic peripheral neuropat...
Enzymes: Sodium-dependent serotonin transporterMethamphetamine Serotonin Reuptake Inhibitor Action Pathway
smpdb.ca/view/SMP0126619Drug actionMethamphetamine (metamfetamine) is a psychostimulant and sympathomimetic drug. It is mainly taken recreationally but can be taken for ADHD and exogenous obesity in the form of a drug called Desoxyn. Methamphetamine induces effects of eup...
Enzymes: Sodium-dependent serotonin transporterClofarabine Action Pathway
smpdb.ca/view/SMP0126495Drug actionThis molecule differs from the other purine analogs by chlorine in the purine ring and fluorine in the ribose moiety.
Enzymes: Sodium/nucleoside cotransporter 2Isocarboxazid Amine Oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126692Drug actionIsocarboxazid, also known as Marplan, is an antidepressant from the monoamine oxidase inhibitors (MAOIs) drug class. This drug is indicated in different disorders like major depression, dysthymic disorder, atypical disorder, panic disord...
Enzymes: Sodium-dependent noradrenaline transporterPhentermine Action Pathway
smpdb.ca/view/SMP0125178Drug actionPhentermine is an oral sympathomimetic anorectic drug used as a short-term adjunct therapy that is included in a regimen of weight reduction in cases of exogenous obesity. Phentermine is indicated, alone or in combination with topiramate...
Enzymes: Sodium-dependent noradrenaline transporterAmine Oxidase Norepinephrine
smpdb.ca/view/SMP0130460PhysiologicalThe monoamine oxidase is an enzyme that catalyzes the oxidative deamination of many amines like serotonin, norepinephrine, epinephrine, and dopamine. There are 2 isoforms of this protein: A and B. The first one is found in cells located ...
Enzymes: Sodium-dependent noradrenaline transporterTranylcypromine Amine Oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126672Drug actionTranylcypromine is a non-hydrazine monoamine oxidase inhibitor belonging to the class of antidepressants called MAOIs. This drug is indicated in the treatment of major depression, dysthymic disorder, and atypical depression. It also is u...
Enzymes: Sodium-dependent noradrenaline transporterPhenelzine Amine Oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126682Drug actionPhenelzine, also known as Nardil, is a monoamine oxidase inhibitor (MAOIs). This drug is used as an antidepressant and it is also effective in the treatment of panic disorder and social anxiety disorder. The monoamine oxidase is an enzym...
Enzymes: Sodium-dependent noradrenaline transporterMinaprine Amine oxidase Norepinephrine Antidepressant Action Pathway
smpdb.ca/view/SMP0126684Drug actionMinaprine is an amino-phenylpyridazine antidepressant. It is indicated in the treatment of various depressive states. Minaprine acts on many targets in the neurons. Firstly, this drug binds as an antagonist to the serotonin type 2 recept...
Enzymes: Sodium-dependent noradrenaline transporter