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Displaying results 291 - 300 of 1203 in total
  1. Target

    Glucocorticoid receptor

    go.drugbank.com/bio_entities/BE0000794
    TargetHumans

    Receptor for glucocorticoids (GC) (PubMed:27120390, PubMed:37478846).

    Polypeptides: Glucocorticoid receptorSynonyms: Nuclear receptor subfamily 3 group C member 1
  2. Target

    Ferripyoverdine receptor

    go.drugbank.com/bio_entities/BE0001305
    TargetPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)

    Receptor for the siderophore ferripyoverdine.

    Polypeptides: Ferripyoverdine receptorSynonyms: Ferripyoverdine receptor precursor
  3. Target

    Leptin receptor

    go.drugbank.com/bio_entities/BE0003376
    TargetHumans

    Receptor for hormone LEP/leptin (Probable) (PubMed:22405007).

    Polypeptides: Leptin receptorSynonyms: OB receptor
  4. Target

    Motilin receptor

    go.drugbank.com/bio_entities/BE0003521
    TargetHumans

    Receptor for motilin

    Polypeptides: Motilin receptorSynonyms: G protein-coupled receptor 38
  5. Target

    Transferrin receptor

    go.drugbank.com/bio_entities/BE0004850
    TransporterTargetHumans

    Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes (PubMed:26214738, PubMed:41772062). … The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor.

    Polypeptides: Transferrin receptor protein 1, Transferrin receptor protein 2Synonyms: Transferrin receptor 1
  6. Target

    Dopamine receptor

    go.drugbank.com/bio_entities/BE0009376
    TargetHumans

    Also acts as a receptor for D-lysergic (LSD) psychedelic drug (PubMed:39094559) … Also acts as a receptor for D-lysergic (LSD) psychedelic drug (PubMed:40683247)

    Polypeptides: Dopamine receptor D1, Dopamine receptor D2Synonyms: Dopamine D1 receptor, Dopamine D2 receptor
  7. Drug

    Famtozinameran

    go.drugbank.com/drugs/DB17088
    ApprovedInvestigational

    The Omicron variant of SARS-CoV-2 is a variant of concern that was first reported in November 2021. It tends to cause less severe disease but is significantly more virulent than both the original virus and earlier variants (e.g. Delta). ...

  8. Drug

    Tavolixizumab

    go.drugbank.com/drugs/DB15042
    Investigational

    Tavolixizumab is under investigation in clinical trial NCT02318394 (A Phase 1 Study of MEDI0562 in Adult Subjects With Selected Advanced Solid Tumors).

    Synonyms: IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENSTNFRSF4 (TUMOR NECROSIS FACTOR RECEPTOR (TNFR) SUPERFAMILY MEMBER 4, OX40, CD134)), HUMANIZED AND CHIMERIC MONOCLONAL ANTIBODY GAMMA1 HEAVY CHAIN (1-451) (CHIMERIC
  9. Target

    Androgen receptor

    go.drugbank.com/bio_entities/BE0000132
    TargetHumans

    activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor

    Polypeptides: Androgen receptorSynonyms: Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
  10. Target

    Calcitonin receptor

    go.drugbank.com/bio_entities/BE0000431
    TargetHumans

    CALCR interacts with receptor-activity-modifying proteins RAMP1, 2 and 3 to form receptor complexes AMYR1, 2 and 3, respectively (PubMed:35324283, PubMed:38603770). … IAPP, CT and CGRP1 activate CALCR and AMYRs with distinct modes of receptor activation resulting in specific phenotypes (PubMed:35324283, PubMed:38603770).

    Polypeptides: Calcitonin receptorFunction: amylin receptor activity