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Displaying results 3071 - 3080 of 8694 in total

Drug
Cefixime
go.drugbank.com/drugs/DB00671
ApprovedInvestigational
[A232920, A232925, A232930] Cefixime is a broad-spectrum antibiotic and an orally-active third-generation semisynthetic cephalosporin. … [A263026] However, cefixime is not recommended as a first-line of treatment for uncomplicated urogenital, anorectal, or pharyngeal gonorrhea because cefixime does not provide the same bactericidal effect
Categories: Antibacterials for Systemic Use, Antiinfectives for Systemic UseProducts: Sorcelif 100 mg/5 ml Granulat zur Herstellung einer Suspension zum Einnehmen
Drug
Baxdrostat
go.drugbank.com/drugs/DB19090
ApprovedInvestigational
On May 18, 2026, baxdrostat was approved by the FDA as a first-in-class aldosterone synthase inhibitor for the treatment of hypertension in combination with other antihypertensive drugs [L56189]. … Baxdrostat offers an upstream alternative to traditional mineralocorticoid receptor antagonists (MRAs), such as [spironolactone], which often induce off-target endocrine side effects like gynecomastia
Categories: P-glycoprotein substrates, Cytochrome P-450 Substrates
Drug
Ergotamine
go.drugbank.com/drugs/DB00696
Approved
It is an alpha-1 selective adrenergic agonist and is commonly used in the treatment of migraine disorders.
Mixtures: Cafergot Pb Tab, Cafergot Pb SupCategories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates
Drug
Metamizole
go.drugbank.com/drugs/DB04817
ApprovedInvestigationalWithdrawn
Approvals of the NDA's for metamizole drug products were withdrawn on June 27, 1977 (see the Federal Register of June 17, 1977, 42 FR 30893).
Categories: Cytochrome P-450 CYP2B6 Inducers, Cytochrome P-450 CYP3A Inducers
Drug
Ketoconazole
go.drugbank.com/drugs/DB01026
ApprovedInvestigational
[A181802,T116] Ketoconazole was first approved in an oral formulation for systemic use by the FDA in 1981. … Ketoconazole is an imidazole antifungal agent used in the prevention and treatment of a variety of fungal infections.
Categories: Antifungals for Topical Use, Antimycotics for Systemic UseProducts: REKET - KETOCONAZOLCREMA 2%, REKET - KETOCONAZOL TABLETAS X 200 MG
Drug
Alimemazine
go.drugbank.com/drugs/DB01246
ApprovedVet approvedWithdrawn
A phenothiazine derivative that is used as an antipruritic.
Categories: Antihistamines for Systemic Use
Drug
Amyl Nitrite
go.drugbank.com/drugs/DB01612
Approved
As an inhalant, it also has psychoactive effect which has led to illegal drug use. … Amyl Nitrite is an antihypertensive medicine. Amyl nitrite is employed medically to treat heart diseases such as angina and to treat cyanide poisoning.
Drug
Iloperidone
go.drugbank.com/drugs/DB04946
ApprovedInvestigational
Iloperidone is a benzisoxazole [A263557] and an atypical antipsychotic agent that was first approved by the FDA on May 6, 2009. … [A3024] It is considered to be a second-generation antipsychotic drug [A263552] with multiple receptor binding profile, although it shows high affinity towards 5-HT<sub>2A</sub> and dopamine D2 receptors
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Substrates
Drug
Etonogestrel
go.drugbank.com/drugs/DB00294
ApprovedInvestigational
Etonogestrel molecule is a 3-ketodesogestrel or 19-nortestosterone which is a synthetic biologically active metabolite of progestin desogestrel. The first product including etonogestrel was developed by the Merck subsidiary Organon and F...
Categories: Hormonal Contraceptives for Systemic Use, Cytochrome P-450 SubstratesProducts: Implanon NXT 68 mg Implantat zur subkutanen Anwendung
Drug
Riluzole
go.drugbank.com/drugs/DB00740
ApprovedInvestigational
A glutamate antagonist (receptors, glutamate) used as an anticonvulsant (anticonvulsants) and to prolong the survival of patients with amyotrophic lateral sclerosis.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A1 Substrates