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Displaying results 3071 - 3080 of 3180 in total

Drug
Cefradine
go.drugbank.com/drugs/DB01333
ApprovedWithdrawn
A semi-synthetic cephalosporin antibiotic.
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 Inducers
Drug
Vecuronium
go.drugbank.com/drugs/DB01339
ApprovedInvestigational
Monoquaternary homolog of pancuronium. A non-depolarizing neuromuscular blocking agent with shorter duration of action than pancuronium. Its lack of significant cardiovascular effects and lack of dependence on good kidney function for el...
Categories: P-glycoprotein substrates
Drug
Mestranol
go.drugbank.com/drugs/DB01357
ApprovedWithdrawn
The 3-methyl ether of ethinyl estradiol. It must be demethylated to be biologically active. It is used as the estrogen component of many combination ORAL contraceptives.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 Substrates
Drug
Penbutolol
go.drugbank.com/drugs/DB01359
ApprovedInvestigationalWithdrawn
Penbutolol is a drug in the beta-blocker class used to treat hypertension. Penbutolol binds both beta-1 and beta-2 adrenergic receptors, rendering it a non-selective beta-blocker. Penbutolol can act as a partial agonist at beta adrenergi...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 Substrates
Drug
Paramethasone
go.drugbank.com/drugs/DB01384
Experimental
A glucocorticoid with the general properties of corticosteroids. It has been used by mouth in the treatment of all conditions in which corticosteroid therapy is indicated except adrenal-deficiency states for which its lack of sodium-reta...
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 Substrates
Drug
Yohimbine
go.drugbank.com/drugs/DB01392
ApprovedInvestigationalVet approvedWithdrawn
A plant alkaloid with alpha-2-adrenergic blocking activity. Yohimbine has been used as a mydriatic and in the treatment of impotence. It is also alleged to be an aphrodisiac.
Categories: Cytochrome P-450 Substrates, P-glycoprotein inhibitors
Drug
Danazol
go.drugbank.com/drugs/DB01406
ApprovedInvestigational
A synthetic steroid with antigonadotropic and anti-estrogenic activities that acts as an anterior pituitary suppressant by inhibiting the pituitary output of gonadotropins. It possesses some androgenic properties. Danazol has been used i...
Categories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors
Drug
5-Methoxy-N,N-diisopropyltryptamine
go.drugbank.com/drugs/DB01441
ExperimentalIllicit
N,N-diethyltryptamine, bufotenine, psilocybin and psilocin. … 5-methoxy-N,N-diisopropyltryptamine (5-MeO-DIPT) is a tryptamine derivative and shares many similarities with schedule I tryptamine hallucinogens such as alpha-ethyltryptamine, N,N-dimethyltryptamine,
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesSynonyms: 5-Methoxy-N,N-diisopropyltryptamine, 5-methoxy-N,N-bis(1-methylethyl)-1H-indole-3-ethanamine
Drug
Dimethylthiambutene
go.drugbank.com/drugs/DB01444
ExperimentalIllicit
Dimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, Dimethibutin, Ohton) is an opioid analgesic drug.
Synonyms: N,N,1-trimethyl-3,3-di-2-thienylallylamine, N,N-dimethyl-4,4-di(2-thienyl)-3-buten-2-amine
Drug
Barbital
go.drugbank.com/drugs/DB01483
ExperimentalIllicit
A long-acting barbiturate that depresses most metabolic processes at high doses. It is used as a hypnotic and sedative and may induce dependence. Barbital is also used in veterinary practice for central nervous system depression. Barbita...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers