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Dicloxacillin
go.drugbank.com/drugs/DB00485ApprovedInvestigationalVet approvedOne of the penicillins which is resistant to penicillinase.
Categories: combinations of penicillinsProducts: DICLOXACILINA 250 MG POLVO PARA RECONSTITUIR A SUSPENSIÓN ORAL6-deoxyerythronolide B hydroxylase
go.drugbank.com/bio_entities/BE0001638TargetSaccharopolyspora erythraea (strain NRRL 23338)Catalyzes the conversion of 6-deoxyerythronolide B (6-DEB) to erythronolide B (EB) by the insertion of an oxygen at the 6S position of 6-DEB.
Synonyms: 6-DEB hydroxylaseBromfenac
go.drugbank.com/drugs/DB00963ApprovedWithdrawnTheir well-characterized anti-inflammatory activity, analgesic property, and established safety record have also made NSAIDs an important tool for optimizing surgical outcomes. … Bromfenac is a nonsteroidal anti-inflammatory drug (NSAID) for ophthalmic use. Ophthalmic NSAIDs are becoming a cornerstone for the management of ocular pain and inflammation.
Dihydrostreptomycin
go.drugbank.com/drugs/DB11512ApprovedVet approvedWithdrawnDihydrostreptomycin is an aminoglycoside antibiotic. In humans, the use of dihydrostreptomycin has been associated with ototoxicity. … The FDA withdrew its approval for the use of all drug products containing dihydrostreptomycin sulfate.[L43942]
Synonyms: DST, N,N'''-[(1R,2R,3S,4R,5R,6S)-4-({5-deoxy-2-O-[2-deoxy-2-(methylamino)-a-L-glucopyranosyl]-3-C-(hydroxymethyl)-a-L-lyxofuranosyl}oxy)-2,5,6-trihydroxycyclohexane-1,3-diyl]diguanidinePrimaquine
go.drugbank.com/drugs/DB01087ApprovedInvestigationalAn aminoquinoline that is given by mouth to produce a radical cure and prevent relapse of vivax and ovale malarias following treatment with a blood schizontocide. … It has also been used to prevent transmission of falciparum malaria by those returning to areas where there is a potential for re-introduction of malaria.
Pizotifen
go.drugbank.com/drugs/DB06153ApprovedPizotifen hydrochloride is an active ingredient in Sandomigran, which is used for the prophylactic management of migraines. … Sandomigran is available in a number of countries but is not approved by the FDA nor EMA.
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeProducts: SANDOMIGRAN 0,5 MG KAPLI TABLET, 30 ADETRolicyclidine
go.drugbank.com/drugs/DB01549ExperimentalIllicitRolicyclidine (PCPy) is classified as a dissociative anesthetic agent. It also has hallucinogenic and sedative properties. … Because of its pharmacodynamic similarity to the drug phencyclidine (PCP), rolicyclidine was added to the Schedule I list of illegal drugs in the USA in the 1970s.
Pacritinib
go.drugbank.com/drugs/DB11697ApprovedInvestigational[L40793] The underlying cause of primary MF is unknown, but secondary MF can arise in patients with a history of polycythemia vera or essential thrombocythemia. … Pacritinib is an inhibitor of both wild-type and mutant (V617F) JAK2, as well as FMS-like tyrosine kinase 3 (FLT3), which was granted accelerated approval by the FDA in February 2022 for the treatment
Sulfaphenazole
go.drugbank.com/drugs/DB06729ApprovedSulfaphenazole is a sulfonamide antibacterial.
Categories: combinations of sulfonamidesDigitoxin
go.drugbank.com/drugs/DB01396ApprovedWithdrawnA cardiac glycoside sometimes used in place of digoxin. It has a longer half-life than digoxin; toxic effects, which are similar to those of digoxin, are longer lasting.
Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Compounds used in a research, industrial, or household setting