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Mequinol
go.drugbank.com/drugs/DB09516ApprovedWithdrawnIt is used as an inhibitor for acrylic monomers and acrylonitirles, as a stabilizer for chlorinated hydrocarbons and ethyl cellulose, as an ultraviolet inhibitor, as a chemical intermediate in the manufacture … It is found as an active ingredient in topical drugs used for skin depigmentation indicated for the treatment of solar lentigines.
Categories: Compounds used in a research, industrial, or household settingProlyl 3-hydroxylase OGFOD1
go.drugbank.com/bio_entities/BE0002210TargetHumansInvolved in stress granule formation
Synonyms: Termination and polyadenylation 1 homolog, 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1Still's Disease
go.drugbank.com/conditions/DBCOND0066232Drugs: TetracosactideSynonyms: Still disease with juvenile onset and/or adult onset, Still's disease with juvenile onset and/or adult onset (disorder)Ajmaline
go.drugbank.com/drugs/DB01426ApprovedWithdrawnAn alkaloid found in the root of Rauwolfia serpentina, among other plant sources. … It is a class Ia antiarrhythmic agent that apparently acts by changing the shape and threshold of cardiac action potentials.
Categories: Ajmaline and derivatives, Antiarrhythmics, Class IProducts: Gilurytmal 5 mg/ml Injektionslösung und Konzentrat zur Herstellung einer InfusionslösungSetmelanotide
go.drugbank.com/drugs/DB11700ApprovedInvestigational[A224449] Earlier attempts at agonizing MC4R (such as LY2112688) lead to successful weight loss, but also an increase in blood pressure and heart rate. … [L24474] It is an agonist of the melanocortin 4 receptor.
Categories: Alimentary Tract and Metabolism, Amino Acids, Peptides, and ProteinsTriflusal
go.drugbank.com/drugs/DB08814ApprovedWithdrawnTriflusal is a 2-acetoxy-4-trifluoromethylbenzoic acid and it is an aspirin chemically-related molecule but not a derivative. … Uriach and Company and even though it is commercialized in different countries it is not approved by the FDA, EMA or HealthCanada.
Categories: Blood and Blood Forming OrgansProducts: GRENDIS 300MG CAPSULEPegcetacoplan
go.drugbank.com/drugs/DB16694ApprovedInvestigational[A235000,A235005] Pegcetacoplan was developed out of a need for an inhibitor of complement mediated hemolysis further upstream of C5. … [A235000] Patients given eculizumab experienced less hemolysis caused by the membrane attack complex, but were still somewhat susceptible to hemolysis caused by C3b opsonization.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsAngle-Closure Glaucoma
go.drugbank.com/conditions/DBCOND0041713Drugs: PilocarpineSynonyms: Glaucoma, Closed-Angle, Closed-angle glaucomaHemoglobin
go.drugbank.com/drugs/DB04945ApprovedInvestigationalWithdrawnIt consists primarily of globin and heme.
Categories: Amino Acids, Peptides, and ProteinsElosulfase alfa
go.drugbank.com/drugs/DB09051ApprovedInvestigationalElosulfase alfa was developed by BioMarin Pharmaceutical Inc. and is marketed under the brand Vimizim™. … Elosulfase alfa is a synthetic version of the enzyme N-acetylgalactosamine-6-sulfatase. It was approved by the FDA in 2014 for the treatment of Morquio syndrome.
Synonyms: Recombinant human N-acetylgalactosamine-6-sulfatase, Recombinant human N-acetylgalactosamine-6-sulfatase (rhGALNS)Categories: Enzymes and Coenzymes, Alimentary Tract and Metabolism