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Eliglustat
go.drugbank.com/drugs/DB09039ApprovedInvestigational[L41404,A7634] Eliglustat was approved by the FDA in August 2014 as an oral substrate reduction therapy for the first-line treatment of type 1 Gaucher disease. … [A3752,L41404] Gaucher disease is a rare genetic disorder characterized by the deficiency of acid β-glucosidase, an enzyme that converts glucosylceramide into glucose and ceramide.
Synonyms: N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-pyrrolidinyl)-2-propanyl]octanamideProducts: ELUXAT 84 MG SERT KAPSÜL, CERDELGA® 84 MG CÁPSULA DURACopper Cu-64
go.drugbank.com/drugs/DB13980ApprovedCopper-64 is a radiopharmaceutical usually found in the +2 oxidation state as the complexes including the +1 state tend to be more unstable. … [T604] It is used in molecular radiotherapy and positron emission tomography.
Synonyms: Copper Cu-64, Copper, Cu-64Morphine
go.drugbank.com/drugs/DB00295ApprovedInvestigationalMorphine was granted FDA approval in 1941.[L12114] … Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805.[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse.
Synonyms: (7R,7AS,12bs)-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinoline-7,9-diol, (5R,6S,9R,13S,14R)-4,5-epoxy-N-methyl-7-morphinen-3,6-diolProducts: Oramorph 10 mg - orale Lösung in Einzeldosisbehältern, Oramorph 30 mg - orale Lösung in EinzeldosisbehälternRibavirin
go.drugbank.com/drugs/DB00811ApprovedInvestigationalCombination therapy of ribavirin and [DB00008] results in the SVR of 44% in patients with genotype 1 infection and 70% in patients with genotype 2-6. … Addition of weight-based ribavirin to Technivie therapy increased sustained virologic response after 12 weeks of daily therapy (SVR12) from 90% to 97% in patients with HCV genotype 1a and 90.9% to 100%
Mixtures: Rebetron Ready To Use Solution (albumin(human)free) (6000000 Iu/ml and 200mg Capsules), Rebetron Solution (albumin (human) Free) (18 Miu Multi-dose Pen / 200mg Capsules)Products: REBETOL 200 MG KAPSUL, 84 ADET, VIRON 200 MG SERT KAPSUL, 84 ADETPotassium chloride
go.drugbank.com/drugs/DB00761ApprovedInvestigationalWithdrawnThe FDA withdrew its approval for the use of all solid oral dosage form drug products containing potassium chloride that supply 100 mg or more of potassium per dosage unit, except for controlled-release … A white crystal or crystalline powder used as an electrolyte replenisher, in the treatment of hypokalemia, in buffer solutions, and in fertilizers and explosives.
Mixtures: PISA, SOLUCION HT PISAInternational brands: Kaon-CL 10Fentanyl
go.drugbank.com/drugs/DB00813ApprovedIllicitInvestigationalVet approved[A179542] In 2017, 47600 overdose deaths in the United States involved some opioid (over 2/3 of all overdose deaths).[L6748] Opioid overdoses kill an average of 11 Canadians daily. … [L6751] Fentanyl was FDA approved in 1968.[Label,L6598,L6601,L6604,L6607,L922,L6610,L6613]
Synonyms: N-phenethyl-4-(N-propionylanilino)piperidine, N-(1-phenethyl-4-piperidinyl)-N-phenylpropionamideProducts: FENTANYL 0,05 MG/ML 10 ML SOLÜSYON İÇEREN IV AMPUL, 50 ADET, FENTANEST 500 MG/10 ML IV ENJEKSİYONLUK ÇÖZELTİ (10 ADET)Acylcarnitine 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoylcarnitine
smpdb.ca/view/SMP0123535Metabolic-1-en-1-yl]-5-oxocyclopentyl]heptanoylcarnitine. … inner membrane to once again form 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoyl-CoA and L-carnitine. 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreAcylcarnitine (5Z)-7-{2-[(1E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl}hept-5-enoylcarnitine
smpdb.ca/view/SMP0123569Metabolic-1-en-1-yl]-3,5-dihydroxycyclopentyl}hept-5-enoylcarnitine. … inner membrane to once again form (5Z)-7-{2-[(1E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl}hept-5-enoyl-CoA and L-carnitine. (5Z)-7-{2-[(1E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreIopromide
go.drugbank.com/drugs/DB09156Approved[A260751] Approved by the FDA in 1995 and Health Canada in 1994 under the brand name ULTRAVIST, iopromide is used in radiological diagnosis, including, but not limited to, intra-arterial digital subtraction … [A260751] Although the mechanism is unclear, women and outpatients tend to have a higher incidence of adverse events compared to other population groups.
Synonyms: N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[(methoxyacetyl)amino]-N-methylisophthalamideCategories: Compounds used in a research, industrial, or household settingNaloxone
go.drugbank.com/drugs/DB01183ApprovedInvestigationalVet approved[L33734] Kits commonly include the supplies necessary to treat an overdose in a non-medical setting such as alcohol swabs, syringes, a rescue breathing mask, and instructions for use. … [L33714,L33719] Naloxone was granted FDA approval on 13 April 1971.[L33709]
Synonyms: 1-N-Allyl-14-hydroxynordihydromorphinoneMixtures: Targin 80 mg/40 mg Retardtabletten, OXYCODON/NALOX KRUGM 80/40