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Blinatumomab
go.drugbank.com/drugs/DB09052ApprovedInvestigationalBlinatumomab is a BiTE-class (bi-specific T-cell engager) constructed monoclonal antibody formed by the recombinant fusion of an anti-CD3 single-chain variable fragment (scFV) and an anti-CD19 scFV through … It was first approved by the FDA in December 2014 for the treatment of CD19-positive B-cell precursor acute lymphoblastic leukemia (ALL) in relapsed and refractory patients.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsEfanesoctocog alfa
go.drugbank.com/drugs/DB16662ApprovedInvestigational[L45379] The use of FVIII replacement products is beneficial in patients with hemophilia A; however, their quality of life can be affected due to frequent doses. … Endogenous VWF protects FVIII from degradation but also sets a half-life of approximately 15 to 19 h.
Categories: Amino Acids, Peptides, and ProteinsExacerbation of asthma
go.drugbank.com/conditions/DBCOND0022084Synonyms: Other and unspecified asthmaNuclear factor NF-kappa-B
go.drugbank.com/bio_entities/BE0004903TargetHumansThe NF-kappa-B p50-p50 homodimer is a transcriptional repressor, but can act as a transcriptional activator when associated with BCL3. … The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity
Synonyms: Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1Venous Thromboembolism
go.drugbank.com/conditions/DBCOND0000676Drugs: Acetylsalicylic acid · Betrixaban · Dabigatran etexilate · Dalteparin · Nadroparin · Rivaroxaban +1 moreSynonyms: Acute embolism and thrombosis of unspecified veinJoint sprains
go.drugbank.com/conditions/DBCOND0101640Drugs: EscinSynonyms: (Sprains and strains NOS) or (sprain: [joint NOS] or [ligament NOS] or [muscle NOS] or [rectus sprain] or [tendon NOS]) or (tendon rupture NOS)Ocular hyperemia
go.drugbank.com/conditions/DBCOND0095202Drugs: ChlorpheniramineSynonyms: Conjunctival and scleral injectionGluconic Acid
go.drugbank.com/drugs/DB13180ApprovedInvestigationalCommonly found in salts with sodium and calcium. Gluconic acid or gluconate is used to maintain the cation-anion balance on electrolyte solutions.
Mixtures: Normosol-R and Dextrose, Plasma-Lyte 148 and dextroseCongenital Adrenal Hyperplasia (CAH)
go.drugbank.com/conditions/DBCOND0033416Drugs: Betamethasone · Bupivacaine · Cortisone acetate · Crinecerfont · Dexamethasone · Hydrocortisone +7 moreSynonyms: CAH - Congenital Adrenal Hyperplasia, Congenital Adrenal Hyperplasia (CAH)Coronary Artery Disease (CAD)
go.drugbank.com/conditions/DBCOND0032937Synonyms: CAD, Coronary Artery Disease (CAD)