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Enzalutamide
go.drugbank.com/drugs/DB08899ApprovedInvestigationalCompared to the average time of 10 to 15 years for a drug to go from pre-clinical to clinical studies, enzalutamide was developed relatively rapidly.[A252667] … [L40639] It is a second-generation antiandrogen agent that the FDA approved on August 31, 2012.
Categories: Heterocyclic Compounds, 1-Ring, P-glycoprotein inhibitorsProducts: XTANDI ® 40 MG, XTANDI® 40 MGEthambutol
go.drugbank.com/drugs/DB00330ApprovedInvestigational[A229048] It was developed out of a need for therapies active against isoniazid resistant strains of _Mycobacterium tuberculosis_.[A229048] Ethambutol was granted FDA approval on 6 November 1967. … Ethambutol is a bacteriostatic agent indicated alongside medications such as [isoniazid], [rifampin], and [pyrazinamide] in the treatment of pulmonary tuberculosis.
Mixtures: RIFAMPICIN 150 MG/ISONIAZID 75 MG/PYRAZINAMIDE 400 MG/ETHAMBUTOL 275 MG, RIFAMPICIN 150 MG/ISONIAZID 75 MG/PYRAZINAMIDE 400 MG/ETHAMBUTOL 275 MGCategories: MATE 1 Substrates, MATE 2 SubstratesAcemetacin
go.drugbank.com/drugs/DB13783ApprovedInvestigational[A31352] In clinical trials, acemetacin exhibits a better gastric tolerability compared to its active metabolite indometacin.[T50] It was developed by E. … It is a potent non-steroidal anti-inflammatory drug, derived from the indol-3-acetic acid, whose activity is thought to be mainly through its active metabolite indomethacin.
Categories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 2-RingProducts: RANTUDİL 90 MG UZATILMIŞ SALIMLI KAPSÜL, 10 ADET, RANTUDIL® 60 MG CAPSULASGinger
go.drugbank.com/drugs/DB10344ApprovedInvestigationalGinger allergenic extract is used in allergenic testing.
Mixtures: B-Nexa, B-NexaProducts: Zingiber officinale dry extract 5%, Zinaxin Ev. Ext 77 Ginger ExtractTriptorelin
go.drugbank.com/drugs/DB06825ApprovedInvestigationalVet approvedTriptorelin is a synthetic decapeptide agonist analog of luteinizing hormone releasing hormone (LHRH).
Synonyms: (6-D-Tryptophan)luteinizing hormone-releasing hormone, (D-Trp6)-GnRHProducts: GONAPEPTYL 0,1 MG/ML ENJEKSİYONLUK ÇÖZELTİ, 1 ADET, DECAPEPTYL DEPOT 3,75 MG INJEKSIYONLUK SUSPANSIYON ICIN TOZ VE COZUCU, 1 ADETLynestrenol
go.drugbank.com/drugs/DB12474ApprovedWithdrawnLynestrenol is a progestin and prodrug of [norethisterone].
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: ORGAMETRİL 5 MG TABLET, 30 ADETAdalimumab
go.drugbank.com/drugs/DB00051ApprovedInvestigationalIt is produced by recombinant DNA technology using a mammalian cell expression system. … [A39984,A39999] It was originally launched by Abbvie in the U.S. and approved in 2002 by the FDA.[A39983] This drug is frequently known as _Humira_.
Products: AMGEVITA 40 MG ILO I E PEN, HUMIRA 40MG ILO I E FERLorlatinib
go.drugbank.com/drugs/DB12130ApprovedInvestigationalinclude lorlatinib as a first-line treatment option in advanced ALK-positive NSCLC. … It was subsequently approved by the EMA in 2019 for the treatment of select patients with previously treated advanced ALK-positive non-small cell lung cancer, followed by an expanded approval in 2022 to
Categories: MATE 1 Inhibitors, Heterocyclic Compounds, 1-RingProducts: LORBRENA® 100 MG, LORVIQUA (TABLETS 100 MG)Group 10 secretory phospholipase A2
go.drugbank.com/bio_entities/BE0000070TargetEnzymeHumansSecretory calcium-dependent phospholipase A2 that primarily targets extracellular phospholipids (PubMed:12021277, PubMed:9188469). Hydrolyzes the ester bond of the fatty acyl group attached at sn-2 position of phospholipids with preferen...
Polypeptides: Group 10 secretory phospholipase A2Synonyms: Phosphatidylcholine 2-acylhydrolase 10Interleukin-10 receptor subunit alpha
go.drugbank.com/bio_entities/BE0014391TargetHumansCell surface receptor for the cytokine IL10 that participates in IL10-mediated anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Upon binding to IL10, induces a conformational change in IL10RB, all...
Polypeptides: Interleukin-10 receptor subunit alphaSynonyms: IL-10 receptor subunit alpha, Interleukin-10 receptor subunit 1