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Displaying results 311 - 320 of 10000 in total
  1. Drug

    Ustekinumab

    go.drugbank.com/drugs/DB05679
    ApprovedInvestigational

    L52830] and Wezlana [L52073] in Canada, and Uzpruvo in the EU. … Ustekinumab is a human immunoglobulin (Ig) G1 kappa monoclonal antibody directed against interleukin(IL)-12 and IL-23, which are cytokines that are involved in immune and inflammatory responses.

    Products: Stelara Solution for Injection in Pre-Filled Syringe 90 mg/1 mL, STELARA 90MG/1ML SOLUTION FOR INJECTION IN PREFILLED SYRINGE
  2. Drug

    Protamine

    go.drugbank.com/drugs/DB13700
    ApprovedInvestigationalWithdrawn

    Products: PROTAMİN ICN 5000 IU/5ML IV KULLANIM İÇİN ENJEKSİYONLUK ÇÖZELTİ İÇEREN AMPUL, 1 ADET, PROTAMYN 1000® UI/ML AMPOLLA
  3. Drug

    Calcium gluconate

    go.drugbank.com/drugs/DB11126
    ApprovedInvestigationalVet approved

    Calcium gluconate is used as mineral supplement and medication when there is insufficient calcium in the diet. … Supplementation may be done to treat or prevent osteoporosis or rickets, consequences of hypocalcemia. It can also be taken by mouth but is not recommended by injection into a muscle.

    Mixtures: Multiple Electrolyte Additive Inj, ELETTROLITICA DI REINTEGRAZIONE CON GLUCOSIO E SODIO GLUCONATO FKISynonyms: D-gluconic acid, calcium salt (2:1)
  4. Drug

    Ofatumumab

    go.drugbank.com/drugs/DB06650
    ApprovedInvestigational

    It is an IgG1κ human monoclonal antibody produced from a recombinant murine cell line (NS0) via transgenic mouse and hybridoma technology. … [L12612] Ofatumumab works by recognizing antigens that are expressed on the tumour cells in certain cancers; however, the antigen is not tumour-specific and can also be found in normal B-cells.

    Products: KESIMPTA SOLUTION FOR INJECTION IN PRE-FILLED PEN 20MG/0.4ML, Bonspri 20mg/0.4mL Solution for Injection in Pre-filled syringe
  5. Target

    Type II secretion system ATPase E

    go.drugbank.com/bio_entities/BE0003292
    TargetVibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

    Acts as a molecular motor to provide the energy that is required for assembly of the pseudopilus and the extrusion of substrates generated in the cytoplasm.

    Polypeptides: Type II secretion system ATPase ESynonyms: T2SS protein E, General secretion pathway protein E
  6. Drug

    Ondansetron

    go.drugbank.com/drugs/DB00904
    ApprovedInvestigationalWithdrawn

    and use, including the development of orally soluble films that are both discreet in administration and less of a burden in comparison to having patients attempt to swallow pills during emesis. … [L5221] The FDA withdrew its approval for the use of all intravenous drug products containing more than 16 mg of ondansetron hydrochloride in a single dose, due to a high risk of QT prolongation.

    Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 3-RingProducts: Zofran 4mg in 2ml Solution for Injection, Zofran 8mg in 4ml Solution for Injection
  7. Drug

    Paliperidone

    go.drugbank.com/drugs/DB01267
    ApprovedInvestigational

    It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism. … Paliperidone is the primary active metabolite of risperidone. The mechanism of action is unknown but it is likely to act via a similar pathway to risperidone.

    Categories: P-glycoprotein inhibitors, P-glycoprotein substratesSynonyms: 9-hydroxyrisperidone
  8. Drug

    Antihemophilic factor human

    go.drugbank.com/drugs/DB13192
    ApprovedInvestigational

    Activation of Factor IX leads to a cascade of signals that results in activation of Factor X, which then results in the conversion of prothrombin to thrombin, and as a result, leads to the conversion of … Endogenous Factor VIII is essential to the clotting process in the body due to its involvement in the clotting cascade where it is responsible for acting as a co-factor to Factor IX.

    Mixtures: IMMUNATE 500 IU/375 IU IV INFUZYONLUK TOZ ICEREN FLAKON, 1 ADET, IMMUNATE 1000 IU/750 IU IV INFUZYONLUK TOZ ICEREN FLAKON, 1 ADETCategories: Hemophilia A
  9. Drug

    Potassium hydroxide

    go.drugbank.com/drugs/DB11153
    Approved

    Potassium hydroxide is used in food to adjust pH, as a stabilizer, and as a thickening agent. … Also commonly referred to as _caustic potash_, it is a potent base that is marketed in several forms including pellets, flakes, and powders.

    Synonyms: hydroxyde de potassiumMixtures: Vamin N, NUTRIFLEX PERI IN 2000ML TWIN-FLEX
  10. Drug

    Beroctocog alfa

    go.drugbank.com/drugs/DB14473
    ApprovedInvestigational

    Mixtures: OPTIVATE(R), HAEMATE PProducts: KOATE-DVI 250 IU/5 ML IV ENJEKSİYON İÇİN LİYOFİLZE TOZ İÇEREN FLAKON, FEIBA 1000 U IV INFUZYON ICIN LIYOFILIZE TOZ ICEREN FLAKON, 1 ADET