Search

Displaying results 311 - 320 of 2828 in total
  1. Target

    Bacitracin transport permease protein BcrC

    go.drugbank.com/bio_entities/BE0009707
    TransporterBacillus licheniformis

    Part of the binding-protein-dependent transport system for bacitracin that confer resistance to this antibiotic; probably responsible for the translocation of the substrate across the membrane.

    Polypeptides: Bacitracin transport permease protein BcrC
  2. Target

    Cationic amino acid transporter 4

    go.drugbank.com/bio_entities/BE0000052
    TargetHumans

    Involved in the transport of the cationic amino acids (arginine, lysine and ornithine)

    Polypeptides: Cationic amino acid transporter 4Function: basic amino acid transmembrane transporter activity
  3. Target

    Organic cation/carnitine transporter 2

    go.drugbank.com/bio_entities/BE0000106
    TargetTransporterHumans

    Also transports organic cations such as tetraethylammonium (TEA) without the involvement of sodium. … Sodium-ion dependent, high affinity carnitine transporter. Involved in the active cellular uptake of carnitine.

    Polypeptides: Organic cation/carnitine transporter 2Function: (R)-carnitine transmembrane transporter activity
  4. Target

    Cationic amino acid transporter 3

    go.drugbank.com/bio_entities/BE0000136
    TargetHumans

    The transport is sodium ions- and pH-independent, moderately trans-stimulated and is mediated by passive diffusion (PubMed:11591158)

    Polypeptides: Cationic amino acid transporter 3Synonyms: Cationic amino acid transporter y+
  5. Target

    Excitatory amino acid transporter 2

    go.drugbank.com/bio_entities/BE0000884
    TargetTransporterHumans

    Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion (PubMed:14506254). … Mediates Cl(-) flux that is not coupled to amino acid transport; this avoids the accumulation of negative charges due to aspartate and Na(+) symport (PubMed:14506254).

    Polypeptides: Excitatory amino acid transporter 2Synonyms: Glutamate/aspartate transporter II, Sodium-dependent glutamate/aspartate transporter 2
  6. Target

    Choline transporter-like protein 2

    go.drugbank.com/bio_entities/BE0002183
    TransporterHumans

    Choline/H+ antiporter, mainly in mitochondria (PubMed:10677542, PubMed:20665236, PubMed:23651124, PubMed:33789160). Also acts as a low-affinity ethanolamine/H+ antiporter, regulating the supply of extracellular ethanolamine (Etn) for the...

    Polypeptides: Choline transporter-like protein 2Function: choline transmembrane transporter activity
  7. Target

    Choline transporter-like protein 3

    go.drugbank.com/bio_entities/BE0002184
    TransporterHumans

    Polypeptides: Choline transporter-like protein 3Function: choline transmembrane transporter activity
  8. Target

    Excitatory amino acid transporter 4

    go.drugbank.com/bio_entities/BE0002270
    TargetHumans

    Functions as a symporter that transports one amino acid molecule together with two or three Na(+) ions and one proton, in parallel with the counter-transport of one K(+) ion. … Sodium-dependent, high-affinity amino acid transporter that mediates the uptake of L-glutamate and also L-aspartate and D-aspartate (PubMed:26690923, PubMed:7791878).

    Polypeptides: Excitatory amino acid transporter 4Synonyms: Sodium-dependent glutamate/aspartate transporter
  9. Drug

    Chlorothiazide

    go.drugbank.com/drugs/DB00880
    ApprovedInvestigationalVet approved

    A thiazide diuretic with actions and uses similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p812)

    Categories: Membrane Transport Modulators, Genito Urinary System and Sex Hormones
  10. Drug

    Rintatolimod

    go.drugbank.com/drugs/DB16425
    Investigational

    Synonyms: 5'-INOSINIC ACID, HOMOPOLYMER, COMPLEX WITH 5'-CYTIDYLIC ACID POLYMER WITH 5'-URIDYLIC ACID (1:1)