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Displaying results 321 - 330 of 7536 in total
  1. Target

    Cocaine esterase

    go.drugbank.com/bio_entities/BE0001413
    TargetEnzymeRhodococcus sp. (strain MB1 Bresler)

    Hydrolyzes cocaine to benzoate and ecgonine methyl ester, endowing the bacteria with the ability to utilize cocaine as a sole source of carbon and energy for growth, as this bacterium lives in the rhizosphere of coca plants. Also efficie...

    Polypeptides: Cocaine esterase
  2. Target

    Esterase EstB

    go.drugbank.com/bio_entities/BE0003305
    TargetPseudomonas marginata

    Lacks beta-lactamase activity; it hydrolyzes the ester bond of cephalosporin substrates but there is no opening of the beta-lactam ring observed.

    Polypeptides: Esterase EstB
  3. Drug

    5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine

    go.drugbank.com/drugs/DB07140
    Experimental

    Synonyms: 5-[(3R)-3-(5-methoxybiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
  4. Drug

    Ipratropium

    go.drugbank.com/drugs/DB00332
    ApprovedInvestigational

    [A176957] Ipratropium as a therapeutic agent was developed by Boehringer Ingelheim and its first monotherapy product was FDA approved in 1986, while the combination product of ipratropium and [albuterol

    Mixtures: BERODUAL N METERED DOSE INHALER, BERODUAL N METERED DOSE INHALERCategories: Agents to Treat Airway Disease
  5. Drug

    Vitamin E

    go.drugbank.com/drugs/DB00163
    ApprovedInvestigationalNutraceuticalVet approved

    Though this research is so far inconclusive, vitamin E remains a popular supplement and is generally considered safe by the FDA[FDA Label]. … In 1922, vitamin E was demonstrated to be an essential nutrient[A32448].

    Mixtures: Doctor's Choice Brand for Men, Prenatal Vitamin No 53 Iron Fum Folic Acid Docusate CA DHAProducts: Now E-400, Vitamin E Cap 200iu Nf Natural Source
  6. Drug

    Ubidecarenone

    go.drugbank.com/drugs/DB09270
    ApprovedInvestigationalNutraceutical

    [L1062] Ubidecarenone is sold as a dietary supplement and is not FDA approved as a drug - it is not meant to treat, cure or prevent any disease. … FDA does not approve this dietary supplements before sold nor regulate the manufacturing process.[L1063]

    Mixtures: Shine CO-Q Plus, Co-q10 M.R.B. 60mgSynonyms: Co Enzyme Q10, Co-Enzyme Q10
  7. Drug

    TERT-BUTYL 4-({[4-(BUT-2-YN-1-YLAMINO)PHENYL]SULFONYL}METHYL)-4-[(HYDROXYAMINO)CARBONYL]PIPERIDINE-1-CARBOXYLATE

    go.drugbank.com/drugs/DB07013
    Experimental

    Synonyms: TERT-BUTYL 4-({[4-(BUT-2-YN-1-YLAMINO)PHENYL]SULFONYL}METHYL)-4-[(HYDROXYAMINO)CARBONYL]PIPERIDINE-1-CARBOXYLATE
  8. Drug

    5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine

    go.drugbank.com/drugs/DB07142
    Experimental

    Synonyms: 5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine
  9. Indication

    Accelerated Phase Chronic Myelogenous Leukemia (CML)

    go.drugbank.com/conditions/DBCOND0121922
    Drugs: Bosutinib · Dasatinib · Imatinib · Nilotinib · Ponatinib
    Synonyms: Chronic myelogenous leukemia, no ICD-O subtype, Chronic myelogenous leukemia, no ICD-O subtype (morphologic abnormality)
  10. Indication

    Classical Hodgkin's Lymphoma

    go.drugbank.com/conditions/DBCOND0113588
    Drugs: Brentuximab vedotin · Nivolumab
    Synonyms: Hodgkin lymphoma, no ICD-O subtype, Hodgkin lymphoma, no ICD-O subtype (morphologic abnormality)