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Displaying results 321 - 330 of 10000 in total
  1. Pathway

    Acylcarnitine 11-{3,4-dimethyl-5-[(1E)-pent-1-en-1-yl]furan-2-yl}undecanoylcarnitine

    smpdb.ca/view/SMP0123498
    Metabolic

    11-{3,4-dimethyl-5-[(1E)-pent-1-en-1-yl]furan-2-yl}undecanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 11-{3,4-dimethyl-5-[(1E)-pent-1-en-1-yl]furan-2-yl}undecanoyl-CoA reacts with L-carnitine to form 11-{3,4-dimethyl-5-[(1E)-pent-1-en-1-yl]furan-2-yl}undecanoylcarnitine

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  2. Drug

    Fexofenadine

    go.drugbank.com/drugs/DB00950
    ApprovedInvestigational

    [L4269] It is selective for the H<sub>1</sub> receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier[L10779] - this is in contrast to previous first-generation … Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms.

    Products: TELFAST 120MG, TELFAST 120MG FILMTABL
  3. Drug

    Naloxone

    go.drugbank.com/drugs/DB01183
    ApprovedInvestigationalVet approved

    [A234594] More specifically, naloxone has a high affinity for μ-opioid receptors, where it acts as an inverse agonist, causing the rapid removal of any other drugs bound to these receptors. … Notably, if injected into a person not currently using opioid medications, there would be no noticeable effects at all.

    Mixtures: VALORON N RETARD 150/12MG, VALORON N RETARD 150/12MGSynonyms: 1-N-Allyl-14-hydroxynordihydromorphinone
  4. Drug

    Sibutramine

    go.drugbank.com/drugs/DB01105
    ApprovedIllicitWithdrawn

    It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the United States. … Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity.

    Products: SIBUTRAMINA 15MG, SIBESY(R)10MG CAPSULAS
  5. Drug

    Copper

    go.drugbank.com/drugs/DB09130
    ApprovedInvestigational

    Copper is a transition metal and a trace element in the body. It is important to the function of many enzymes including cytochrome c oxidase, monoamine oxidase and superoxide dismutase [FDA Label]. … Copper is commonly used in contraceptive intrauterine devices (IUD) [L801].

    Mixtures: Copper 3mg Plus Iron & Zinc Tab, Trace Minerals Et/and B12 TabProducts: Chela Copper Tab 3mg, Chelated Copper Supplement - Tab 2mg
  6. Indication

    Hyperkeratosis follicularis et parafollicularis

    go.drugbank.com/conditions/DBCOND0020027
    Drugs: Salicylic acid
    Synonyms: Hyperkeratosis follicularis et parafollicularis, Keratosis follicularis et parafollicularis in cutem penetrans
  7. Drug

    Vinorelbine

    go.drugbank.com/drugs/DB00361
    ApprovedInvestigational

    It was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. It is a third-generation vinca alkaloid. … It was found that there was 4.3-fold variation in vinorelbine clearance across the cohort, suggesting a strong influence of genetics on the clearance of this drug [L2002].

    Products: VINELBINE INJECTION-10MG/ML, NAVELBINE 10MG,INJECTABLE SOLUTION
  8. Drug

    Rizatriptan

    go.drugbank.com/drugs/DB00953
    ApprovedInvestigational

    Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT<sub>1B and 5-HT1D</sub> receptor agonist. … [L46018] Used in the treatment of migraines, rizatriptan was first approved in the US in 1998.

    Synonyms: N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine, N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamineProducts: RIZATRIPTAN EG, MAXALT 10MG
  9. Drug

    Cetirizine

    go.drugbank.com/drugs/DB00341
    ApprovedInvestigational

    Cetirizine, also commonly known as _Zyrtec_, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal … Allergic rhinitis is associated with multiple missed or unproductive days at work and school, problems with sleep, and other difficulties with day to day activities for many individuals [A175057].

    Mixtures: Cetirizine HCl and Pseudoephedrine HCl ER, Cetirizine HCl and Pseudoephedrine HCl ERProducts: H-E-B Allergy Relief, CETIRIZINA EG
  10. Drug

    Panthenol

    go.drugbank.com/drugs/DB11204
    Approved

    Furthermore, it acts as a topical protectant, moisturizer, and has demonstrated anti-inflammatory properties [A32377]. … Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium.

    Mixtures: EH Plus H2CO3 Cool, EH Plus H2CO3 CoolProducts: BABOR BODY LINE THERMAL Firming Body, Babor Body Line Thermal Smooth Effect Body