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Anacaulase
go.drugbank.com/drugs/DB17449ApprovedInvestigational[A256047,A256052,A256057] The EMA approved the use of anacaulase in 2013,[A256047,A256052] and in January 2023, anacaulase received FDA approval.[L44717] … They also require specialized surgical personnel and facilities, and autologous skin grafting may be needed. Therefore, enzymatic alternatives such as anacaulase can lead to better clinical outcomes.
Etacrynic acid
go.drugbank.com/drugs/DB00903ApprovedInvestigationalA compound that inhibits symport of sodium, potassium, and chloride primarily in the ascending limb of Henle, but also in the proximal and distal tubules.
Armodafinil
go.drugbank.com/drugs/DB06413ApprovedInvestigationalArmodafinil consists of the (−)-R-enantiomer of the racemic modafinil. Armodafinil is produced by the pharmaceutical company Cephalon Inc. … Armodafinil is the enantiopure of the wakefulness-promoting agent modafinil (Provigil), and is indicated to improve wakefulness in adult patients with excessive sleepiness associated with obstructive sleep
Mequinol
go.drugbank.com/drugs/DB09516ApprovedWithdrawnIt is found as an active ingredient in topical drugs used for skin depigmentation indicated for the treatment of solar lentigines. … It is used as an inhibitor for acrylic monomers and acrylonitirles, as a stabilizer for chlorinated hydrocarbons and ethyl cellulose, as an ultraviolet inhibitor, as a chemical intermediate in the manufacture
Bovine type I collagen
go.drugbank.com/drugs/DB10771ApprovedInvestigationalExcellagen, a topical gel of bovine type I collagen, is used in the management of wounds including: partial and full- thickness wounds, pressure ulcers, venous ulcers, diabetic ulcers, chronic vascular
Tianeptine
go.drugbank.com/drugs/DB09289InvestigationalCurrently, tianeptine is approved in France and manufactured and marketed by Laboratories Servier SA; it is also marketed in several other European countries under the trade name “Coaxil” as well as in … Tianeptine was discovered and patented by The French Society of Medical Research in the 1960s [L2946].
Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin SyndromeDesflurane
go.drugbank.com/drugs/DB01189ApprovedInvestigationalIt was developed in the late 1980s out of a need for a more rapidly acting and rapidly cleared inhaled anesthetic.[A226883,A226888] Desflurane was granted FDA approval on 18 September 1992.[L30285]
Reboxetine
go.drugbank.com/drugs/DB00234ApprovedInvestigationalWithdrawnReboxetine is an antidepressant drug used in the treatment of clinical depression, panic disorder and ADD/ADHD.
Solriamfetol
go.drugbank.com/drugs/DB14754ApprovedInvestigationalSolriamfetol marketed under the brand name Sunosi by Jazz Pharmaceuticals in the United States is a dopamine and norepinephrine reuptake inhibitor (DNRI) indicated in treating daytime sleepiness associated