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HLX70
go.drugbank.com/drugs/DB16509InvestigationalHLX70, a recombinant humanized anti-S protein monoclonal antibody intended for intravenous infusion, was under investigation in clinical trials NCT05429385 and NCT04561076 to evaluate its safety and pharmacokinetics … The condition targeted by HLX70 in this study is COVID-19.
Dipyrithione
go.drugbank.com/drugs/DB11327Approved[L2611] It is currently used as a pesticide, and not used in any FDA approved drug products. … Dipyrithione, a bactericidal and fungicidal pyrithione derivate, was formulated as Crimanex anti-dandruff shampoo, but is no longer available.
Categories: Heterocyclic Compounds, 1-RingSinecatechins
go.drugbank.com/drugs/DB01266ApprovedInvestigationalNutraceuticalSinecatechins is a botanical drug product for topical use. … It is a partially purified fraction of the water extract of green tea leaves from Camellia sinensis, and is a mixture of catechins and other green tea components.
Synonyms: Polyphenon ECategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingProparacaine
go.drugbank.com/drugs/DB00807ApprovedVet approvedProparacaine is a topical anesthetic drug of the amino ester group. It is found in ophthalmic solutions at a concentration of 0.5% as the hydrochloride salt.
Mixtures: Mydriatic-4International brands: Ak-TaineMephenesin
go.drugbank.com/drugs/DB13583ApprovedWithdrawnMephenesin is a synthetic cresol glyceryl ether which produces transient muscle relaxation and paralysis via central nervous system depression [A32760]. It first entered use in the 1950s.
Synonyms: 3-(O-METHYLPHENOXY)-1,2-PROPANEDIOLMipomersen
go.drugbank.com/drugs/DB05528ApprovedMipomersen sodium, which was known as the investigational drug, isis-301012, is the salt form of a synthetic phosphorothioate oligonucleotide. … It is marketed under the brand name Kynamro in the United States, and the FDA label includes a black box warning of hepatoxicity.
Categories: Apolipoprotein B-100 Synthesis Inhibitor, Compounds used in a research, industrial, or household settingAnileridine
go.drugbank.com/drugs/DB00913ApprovedIllicitWithdrawnAnileridine is a synthetic opioid and strong analgesic medication. It is a narcotic pain reliever used to treat moderate to severe pain.
Categories: Heterocyclic Compounds, 1-RingSynonyms: 1-[2-(4-aminophenyl)ethyl]-4-phenyl-4-piperidinecarboxlic acid ethyl ester, ethyl 1-(2-(4-aminophenyl)ethyl)-4-phenyl-4-piperidinecarboxylateSulisobenzone
go.drugbank.com/drugs/DB11185ApprovedThe UV-filter substance, sulisobenzone (BP-4) is widely used an ingredient in sunscreens and other personal care products [A32927], [L2668]. It falls under the drug category of _benzophenones_. … Sulisobenzone is approved by the FDA in concentrations of up to 10% and in Canada, is approved by Health Canada at the same concentrations [F38].
Synonyms: 2-benzoyl-5-methoxy-1-phenol-4-sulfonic acid, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acidInternational brands: Uvasorb S 5, Uvinul D 5030Umbralisib
go.drugbank.com/drugs/DB14989ApprovedInvestigationalWithdrawnMarginal zone lymphoma is a rare, slowly progressing type of non-Hodgkin lymphoma initially treated with [rituximab] (an anti-CD20 drug), either alone or in combination with chemotherapy. … [A229363] Follicular lymphoma is also treated with rituximab and other chemotherapeutic agents, but may show similar progression.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesSertaconazole
go.drugbank.com/drugs/DB01153ApprovedSertaconazole nitrate is an antifungal medication of the imidazole class. It is available in topical formulations for the treatment of skin infections such as athlete's foot.
Categories: Heterocyclic Compounds, 1-RingProducts: Konzert Cream 2%w/w, ZALAIN® 2% CREMA