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Displaying results 3371 - 3380 of 10000 in total
  1. Drug

    Imidapril

    go.drugbank.com/drugs/DB11783
    Investigational

    Imidapril has been investigated for the treatment of Kidney, Polycystic, Autosomal Dominant.

    Categories: Heterocyclic Compounds, 1-RingProducts: TANATRIL TABLETS 5 mg, TANATRIL TABLETS 10 mg
  2. Target

    Deoxycytidylate 5-hydroxymethyltransferase

    go.drugbank.com/bio_entities/BE0003183
    TargetEnterobacteria phage T4

    Polypeptides: Deoxycytidylate 5-hydroxymethyltransferaseFunction: deoxycytidylate 5-hydroxymethyltransferase activity
  3. Target

    Histone deacetylase 5

    go.drugbank.com/bio_entities/BE0009578
    TargetHumans

    In vitro, it deacetylates lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) (PubMed:10220385). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional reg...

    Polypeptides: Histone deacetylase 5
  4. Target

    Melanocortin receptor 5

    go.drugbank.com/bio_entities/BE0009684
    TargetHumans

    G protein-coupled receptor for melanocyte-stimulating hormones (alpha- beta- and gamma-MSH) and corticotropin/ACTH, which are peptide products of the POMC precursor (PubMed:37524700, PubMed:8396929). Upon activation, couples to G(s) prot...

    Polypeptides: Melanocortin receptor 5
  5. Target

    Pepsin A-5

    go.drugbank.com/bio_entities/BE0009737
    TargetHumans

    Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent

    Polypeptides: Pepsin A-5Synonyms: Pepsinogen-5
  6. Target

    Integrin beta-5

    go.drugbank.com/bio_entities/BE0012746
    TargetHumans

    Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand

    Polypeptides: Integrin beta-5
  7. Drug

    Hydrocortisone succinate

    go.drugbank.com/drugs/DB14545
    ApprovedInvestigational

    Categories: 11-Hydroxycorticosteroids, 17-HydroxycorticosteroidsProducts: SOLU-CORTEF® 100 MG POLVO PARA INYECCION, SOLU-CORTEF FOR INJECTION 100 mg/vial
  8. Drug

    Migalastat

    go.drugbank.com/drugs/DB05018
    ApprovedInvestigational

    [L47036,L47057,L4274,L4278] In the U.S., it is estimated that more than 3,000 people are living with Fabry disease, and an estimated more than 50 percent of these diagnosed patients are currently untreated … [L47036,L47057,L4274,L4278] Globally, it is estimated that approximately 35 to 50 percent of Fabry patients may have amenable GLA variants that are treatable with migalastat.

    Categories: Heterocyclic Compounds, 1-Ring, Alimentary Tract and MetabolismSynonyms: 1-Deoxygalactostatin, 1-Deoxygalactonojirimycin
  9. Drug

    Agalsidase alfa

    go.drugbank.com/drugs/DB15874
    ApprovedInvestigational

    Agalsidase alfa is a recombinant human α-galactosidase A similar to [agalsidase beta]. … [A220343] Agalsidase alfa was granted EMA approval on 3 August 2001.[L16413]

    Categories: Enzymes and Coenzymes, Alimentary Tract and MetabolismSynonyms: alpha-D-galactosidase, alpha-galactosidase A
  10. Drug

    Difluocortolone

    go.drugbank.com/drugs/DB09095
    ApprovedWithdrawn

    Difluocortolone is a potent topical corticosteroid. It is commonly used in dermatology for the reduction of inflammation and itching. … It was submitted to the FDA in July 1984 by the pharmaceutical company Schering AG.[L1082]

    Mixtures: TİNAGEN 1 MG+10 MG/1 G DERİ KREMİ, 15 G, TRODERM 10 MG/G+1 MG/G KREM ,15 GCategories: diflucortolone and antiseptics, Hormones, Hormone Substitutes, and Hormone Antagonists