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Petrolatum
go.drugbank.com/drugs/DB11058ApprovedInvestigationalA colloidal system of semisolid hydrocarbons obtained from petroleum. It is used as an ointment base, topical protectant, and lubricant.
Mixtures: Lubricant PM, retaine PMCategories: Compounds used in a research, industrial, or household settingTerbutaline
go.drugbank.com/drugs/DB00871ApprovedInvestigational[A230328] It is a selective beta-2 adrenergic agonist used as a bronchodilator in asthmatic patients.[A230333,L32093,L32098] Terbutaline was granted FDA approval on 25 March 1974.[L32088]
Products: TERBUTALIN AL 2.5, TERBUTALIN AL RETARDDimethicone
go.drugbank.com/drugs/DB11074ApprovedInvestigationalDimethicone is used as a surfactant, antifoaming agent, carminative in various products such as medical devices, food products, and lubricants. … Dimethicone is a silicone oil that is also known as polydimethylsiloxane (PDMS). It has viscoelastic properties.
Mixtures: A AND A Diaper Rash cream, A and DCategories: Compounds used in a research, industrial, or household settingGuanfacine
go.drugbank.com/drugs/DB01018ApprovedInvestigationalGuanfacine, or BS 100-141,[A189838,A189841] is a selective alpha-A2 adrenergic receptor agonist initially indicated for the treatment of hypertension[L11274] but is now indicated as an extended release
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: Ag-guanfacine XRAripiprazole
go.drugbank.com/drugs/DB01238ApprovedInvestigational[L45859] It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. … Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's.
Categories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesProducts: DM-AR, Ag-aripiprazoleDoxylamine
go.drugbank.com/drugs/DB00366ApprovedInvestigationalVet approvedIt is used in allergies and as an antitussive, antiemetic, and hypnotic. Doxylamine has also been administered in veterinary applications and was formerly used in parkinsonism.
Mixtures: Safetussin PM, Safetussin PMProducts: Aldex ANBetahistine
go.drugbank.com/drugs/DB06698ApprovedInvestigationalIt has a significant impact on both the physical and social functioning of affected individuals. … Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss.
Products: BETAHISTIN AL 6, BETAHISTIN AL 12Parecoxib
go.drugbank.com/drugs/DB08439ApprovedInvestigationalParecoxib is a water-soluble and injectable prodrug of valdecoxib. It is marketed as Dynastat in the European Union. … Parecoxib is a COX2 selective inhibitor in the same category as celecoxib (Celebrex) and rofecoxib (Vioxx).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesSynonyms: N-((p-(5-methyl-3-phenyl-4-isoxazolyl)phenyl)sulfonyl)propionamideGlimepiride
go.drugbank.com/drugs/DB00222ApprovedInvestigationalIt is sometimes classified as a third-generation SU because it has larger substitutions than other second-generation SUs. … [A177703] Compared to other SUs, glimepiride was associated with a lower risk of developing hypoglycemia and weight gain in clinical trials [A177709] as well as fewer cardiovascular effects than other
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C9 SubstratesProducts: GLIMEPIRID AL 1MG, GLIMEPIRID AL 2MGSulpiride
go.drugbank.com/drugs/DB00391ApprovedWithdrawn[A229538] Clinical studies show a greater effect on treating the negative symptoms of schizophrenia rather than positive symptoms at low doses, though the effects are more equal at higher doses.
Categories: P-glycoprotein substratesProducts: SULPIRID AL 50, SULPIRID AL 200