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Displaying results 331 - 340 of 10000 in total
  1. Pathway

    Acylcarnitine (4Z,7Z,10Z,13Z)-15-{3-[(2Z)-pent-2-en-1-yl]oxiran-2-yl}pentadeca-4,7,10,13-tetraenoylcarnitine

    smpdb.ca/view/SMP0123561
    Metabolic

    In forming an acylcarnitine derivative, (4Z,7Z,10Z,13Z)-15-{3-[(2Z)-pent-2-en-1-yl]oxiran-2-yl}pentadeca-4,7,10,13-tetraenoyl-CoA reacts with L-carnitine to form (4Z,7Z,10Z,13Z)-15-{3-[(2Z)-pent-2-en-1 … inner membrane to once again form (4Z,7Z,10Z,13Z)-15-{3-[(2Z)-pent-2-en-1-yl]oxiran-2-yl}pentadeca-4,7,10,13-tetraenoyl-CoA and L-carnitine. (4Z,7Z,10Z,13Z)-15-{3-[(2Z)-pent-2-en-1-yl]oxiran-2-yl}pentadeca

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
  2. Drug

    Fexofenadine

    go.drugbank.com/drugs/DB00950
    ApprovedInvestigational

    [L4269] It is selective for the H<sub>1</sub> receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier[L10779] - this is in contrast to previous first-generation … Fexofenadine is an over-the-counter second-generation antihistamine used in the treatment of various allergic symptoms.

    Products: TELFAST 120MG, TELFAST 120MG FILMTABL
  3. Drug

    Sibutramine

    go.drugbank.com/drugs/DB01105
    ApprovedIllicitWithdrawn

    It is a centrally acting stimulant chemically related to amphetamines thus it is classified as a Schedule IV controlled substance in the United States. … Sibutramine (trade name Meridia in the USA, Reductil in Europe and other countries), usually as sibutramide hydrochloride monohydrate, is an orally administered agent for the treatment of obesity.

    Products: SIBUTRAMINA 15MG, SIBESY(R)10MG CAPSULAS
  4. Drug

    Copper

    go.drugbank.com/drugs/DB09130
    ApprovedInvestigational

    Copper is a transition metal and a trace element in the body. It is important to the function of many enzymes including cytochrome c oxidase, monoamine oxidase and superoxide dismutase [FDA Label]. … Copper is commonly used in contraceptive intrauterine devices (IUD) [L801].

    Mixtures: Copper 3mg Plus Iron & Zinc Tab, Trace Minerals Et/and B12 TabProducts: Chela Copper Tab 3mg, Chelated Copper Supplement - Tab 2mg
  5. Drug

    Vinorelbine

    go.drugbank.com/drugs/DB00361
    ApprovedInvestigational

    It was initially approved in the USA in 1990's for the treatment of NSCLC [L2010]. It is a third-generation vinca alkaloid. … It was found that there was 4.3-fold variation in vinorelbine clearance across the cohort, suggesting a strong influence of genetics on the clearance of this drug [L2002].

    Products: VINELBINE INJECTION-10MG/ML, NAVELBINE 10MG,INJECTABLE SOLUTION
  6. Drug

    Rizatriptan

    go.drugbank.com/drugs/DB00953
    ApprovedInvestigational

    Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT<sub>1B and 5-HT1D</sub> receptor agonist. … [L46018] Used in the treatment of migraines, rizatriptan was first approved in the US in 1998.

    Synonyms: N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]-ethanamine, N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamineProducts: RIZATRIPTAN EG, MAXALT 10MG
  7. Drug

    Cetirizine

    go.drugbank.com/drugs/DB00341
    ApprovedInvestigational

    Cetirizine, also commonly known as _Zyrtec_, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal … Allergic rhinitis is associated with multiple missed or unproductive days at work and school, problems with sleep, and other difficulties with day to day activities for many individuals [A175057].

    Mixtures: Cetirizine HCl and Pseudoephedrine HCl ER, Cetirizine HCl and Pseudoephedrine HCl ERProducts: H-E-B Allergy Relief, CETIRIZINA EG
  8. Drug

    Panthenol

    go.drugbank.com/drugs/DB11204
    Approved

    Furthermore, it acts as a topical protectant, moisturizer, and has demonstrated anti-inflammatory properties [A32377]. … Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium.

    Mixtures: EH Plus H2CO3 Cool, EH Plus H2CO3 CoolProducts: BABOR BODY LINE THERMAL Firming Body, Babor Body Line Thermal Smooth Effect Body
  9. Drug

    Ramipril

    go.drugbank.com/drugs/DB00178
    ApprovedInvestigational

    It is metabolized to ramiprilat in the liver and, to a lesser extent, kidneys. … Ramipril may be used in the treatment of hypertension, congestive heart failure, nephropathy, and to reduce the rate of death, myocardial infarction and stroke in individuals at high risk of cardiovascular

    Mixtures: RAMITANID AL 5MG/6MG, RAMIPRIL HEXAL PL PIR5/6MGCategories: Agents Acting on the Renin-Angiotensin System
  10. Drug

    Quinapril

    go.drugbank.com/drugs/DB00881
    ApprovedInvestigational

    [L8420,L8423] ACE inhibitors are commonly used as a first line therapy in the treatment of hypertension, along with thiazide diuretics or beta blockers. … [L8420,L8423] It is used to treat hypertension and heart failure.

    Mixtures: ACCUZIDE 20 MG/12.5 MG FILM TABLET, 30 ADET, ACCUZIDE FORT 20 MG/25 MG FILM KAPLI TABLET, 30 ADETCategories: Agents Acting on the Renin-Angiotensin System