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Limaprost
go.drugbank.com/drugs/DB09211InvestigationalProstaglandins have a wide variety of actions, including, but not limited to muscular constriction and mediation of inflammation. … Limaprost alfadex has been shown to improve peripheral circulatory failure with a vasodilator action and an antithrombotic effect.
Categories: Prostaglandins EProducts: OPALMON TABLETS 5 ugRadium Ra 223 dichloride
go.drugbank.com/drugs/DB08913ApprovedInvestigationalAs a cation, radium mimics calicum and binds to hydroxyapatite, which is a bone mineral found in areas of high bone turnover as seen in bone metastases. … The FDA label includes a warning that Radium Ra 223 Dichloride should not be used in women who are pregnant or may become pregnant due to the high risk of fetal harm.
Synonyms: Radium chloride Ra-223, Radium (Ra-223) dichlorideProducts: Radium Ra 223 Dichloride, XOFIGO®Cefdinir
go.drugbank.com/drugs/DB00535ApprovedInvestigationalCefdinir was approved by the FDA in 1997 to treat a variety of mild to moderate infections and was initially marketed by Abbvie. … Cefdinir, also known as Omnicef, is a semi-synthetic, broad-spectrum antibiotic belonging to the third generation of the cephalosporin class.
Synonyms: (6R,7R,Z)-7-(2-(2-aminothiazol-4-yl)-2-(hydroxyimino)acetamido)-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid, (6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-hydroxyimino]-acetylamino}-8-oxo-3-vinyl-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acidInternational brands: Omnicef RONO-8539
go.drugbank.com/drugs/DB15325InvestigationalONO-8539 is under investigation in clinical trial NCT01707901 (A Study of the Effect of ONO-8539 on Oesophageal Pain Hypersensitivity in Patients With Non-erosive Reflux Disease).
Categories: Receptors, Prostaglandin E, EP1 Subtype, antagonists & inhibitors, Heterocyclic Compounds, 1-RingNavarixin
go.drugbank.com/drugs/DB11711InvestigationalNavarixin has been investigated for the treatment of Asthma.
Categories: Heterocyclic Compounds, 1-Ring, Receptors, Interleukin-8A, antagonists & inhibitorsCibenzoline
go.drugbank.com/drugs/DB13358InvestigationalCategories: Antiarrhythmics, Class Ia, Antiarrhythmics, Class ICoagulation factor X human
go.drugbank.com/drugs/DB13148ApprovedInvestigationalIt is a two-chain glycoprotein with the molecular weight of approximately 59 kDa [A31472]. … Inherited factor X deficiency is a rare autosomal recessive bleeding disorder that is estimated to occur in 1:1 000 000 individuals up to 1:500 carriers [A31471].
Mixtures: Beriplex P/n 500, Beriplex P/n 1000Categories: Factor X, Factor X, agonistsAldesleukin
go.drugbank.com/drugs/DB00041ApprovedInvestigationalAldesleukin, a lymphokine, is produced by recombinant DNA technology using a genetically engineered E. coli strain containing an analog of the human interleukin-2 gene. … This recombinant form differs from native interleukin-2 in the following ways: a) Aldesleukin is not glycosylated because it is derived from E. coli; b) the molecule has no N-terminal alanine; the codon
Categories: Cytochrome P-450 CYP2E1 Inhibitors, Cytochrome P-450 CYP3A InhibitorsSynonyms: Interleukin-2(2-133),125-ser, 125-L-Serine-2-133-interleukin 2Citalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigationalIt is a racemic bicyclic phthalate derivate and is the only compound with a tertiary amine and 2 nitrogen-containing metabolites among all SSRIs. … [A261316,A14720] Specifically, it has a very minimal effect on dopamine and norepinephrine transportation and virtually no affinity for muscarinic, histaminergic, or GABAergic receptors.
Categories: Monoamine Oxidase A Substrates, P-glycoprotein inhibitorsProducts: CITALOPRAM EG, CITALOPRAM EG STADADarexaban
go.drugbank.com/drugs/DB12289InvestigationalDarexaban has been used in trials studying the prevention and basic science of Japanese, Caucasian, Thromboembolism, Pharmacodynamics, and Pharmacokinetics, among others.
Categories: Factor Xa Inhibitors, Heterocyclic Compounds, 1-Ring