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Piritramide
go.drugbank.com/drugs/DB12492ApprovedWithdrawnPiritramide is under investigation for the treatment of Colon Cancer and Minimal Residual Disease. Piritramide has been investigated for the supportive care of Pain, Postoperative and Postoperative Nausea and Vomiting.
Categories: Heterocyclic Compounds, 1-RingProducts: Dipidolor 7,5 mg/ml InjektionslösungTauroursodeoxycholic acid
go.drugbank.com/drugs/DB08834ApprovedInvestigationalWithdrawnTauroursodeoxycholic acid, also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid [A249070] that is produced in humans at a low concentration. … [A249070] It is a taurine conjugate of [ursodeoxycholic acid] [A249065] with comparable therapeutic efficacy and safety,[A249070] but a much higher hydrophilicity.
Products: TAUROLITE 250 MG 100 KAPSULDrospirenone
go.drugbank.com/drugs/DB01395ApprovedInvestigational[L7973] Most recently, it was approved by both Health Canada and the FDA in combination with [Estetrol] as an oral contraceptive therapy. … Drospirenone is a synthetic progestin commonly found in the popular oral contraceptive, Yaz in combination with [Ethinyl estradiol].
Mixtures: Angeliq 1 mg/2 mg Filmtabletten, ANGELIQ 1 MG/2 MG FILM KAPLI TABLET, 28 ADETCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesTiapride
go.drugbank.com/drugs/DB13025InvestigationalTiapride is a selective D2 and D3 dopamine receptor blocker in the brain.
Products: TIADAL 100 MG/2 ML AMPUL, 12 ADET, TIADAL 100 MG TABLET, 20 ADETMelperone
go.drugbank.com/drugs/DB09224InvestigationalMelperone has been used for a span of greater than 30 years in the European Union [L1316]. … Recently, it has been studied as a treatment of psychosis related to Parkinson's disease [L1316].
Categories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsProducts: MELPERON-NEURAX 10 MG, MELPERON-NEURAX 50 MGCariprazine
go.drugbank.com/drugs/DB06016ApprovedInvestigational[A247100] It works as a partial agonist at central dopamine D2, dopamine D3, and serotonin 5-HT<sub>1A</sub> receptors and as an antagonist at serotonin 5-HT<sub>2A</sub> receptors. … [L41670] It is currently used to treat schizophrenia, and manic or mixed episodes and depressive episodes associated with bipolar I disorder.[L41655,L40198]
Categories: Heterocyclic Compounds, 1-Ring, Serotonin 5-HT1 Receptor AgonistsSynonyms: trans-N-{4-[2-[4-(2,3-dichlorophenyl)piperazine-1-yl]ethyl]cyclohexyl}-N’,N’-dimethylurea hydrochlorideNiclosamide
go.drugbank.com/drugs/DB06803ApprovedInvestigationalVet approvedOver 1 billion people are infected with intestinal nematodes, and many millions are infected with filarial nematodes, flukes, and tapeworms. They are an even greater problem in domestic animals. … Helminths (worms) are multicellular organisms that infect very large numbers of humans and cause a broad range of diseases.
Mixtures: เค.16 ชนิดเม็ดCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 InhibitorsTozinameran
go.drugbank.com/drugs/DB15696ApprovedInvestigationalIt is designed to induce immunity against SARS-CoV-2, the virus responsible for causing COVID-19. … Comirnaty is also approved for use as a fourth booster shot in adults 50 years of age and older.[L41350]
Mixtures: Comirnaty Original & Omicron Ba.4/ba.5, Comirnaty Original & Omicron Ba.4/ba.5Categories: COVID-19 VaccinesTryptophan 5-hydroxylase 2
go.drugbank.com/bio_entities/BE0000080EnzymeTargetHumansNeuron-specific enzyme that catalyzes the conversion of L-tryptophan into 5-hydroxy-L-tryptophan, the rate-limiting step in serotonin production, using Fe(2+) as cofactor and molecular oxygen and tetrahydrobiopterin
Polypeptides: Tryptophan 5-hydroxylase 2Synonyms: Tryptophan 5-monooxygenase 25-hydroxytryptamine receptor 4
go.drugbank.com/bio_entities/BE0000084TargetHumansG protein-coupled receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone and a mitogen (PubMed:10821780, PubMed:16102731, PubMed:35714614, PubMed
Polypeptides: 5-hydroxytryptamine receptor 4Synonyms: 5-HT4, 5-HT-4