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Blinatumomab
go.drugbank.com/drugs/DB09052ApprovedInvestigationala short peptide linker. … [L46991,L46996] Blinatumomab has a short half-life, requiring patients to receive a continuous infusion over 4-week cycles using a portable mini-pump for optimum delivery.[A254826]
Categories: Bispecific CD19-directed CD3-directed T Cell EngagerProducts: BLINCYTO POWDER FOR INFUSION 35 MCG/VIAL, BLINCYTO (Blinatumomab) for injection 35 mcg/vialNilvadipine
go.drugbank.com/drugs/DB06712ApprovedNilvadipine is a calcium channel blocker (CCB) for the treatment of hypertension.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 InhibitorsProducts: Tensan retard 8 mg - Kapseln, ESCOR 8MG RETARDKAPSELNOctenidine
go.drugbank.com/drugs/DB12624InvestigationalOctenidine is under investigation in clinical trial NCT02697162 (Antiseptic-coated Intermittent Urinary Catheter).
Mixtures: Linola sept 1 mg/g + 10 mg/g Wund-Gel, OCTENISEPT ÇÖZELTI, 50 MLCategories: Heterocyclic Compounds, 1-RingSelexipag
go.drugbank.com/drugs/DB11362ApprovedInvestigationalPAH is a relatively rare disease with usually a poor prognosis requiring more treatment options to prolong long-term outcomes.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesProducts: UPTRAVI 200 MCG FILM KAPLI TABLET, 140 ADET, SELPENZA 200 MCG FİLM KAPLI TABLET, 140 ADETBenzbromarone
go.drugbank.com/drugs/DB12319ApprovedWithdrawnBenzbromarone has been used in trials studying the basic science and treatment of Heart Failure, Hyperuricemia, Chronic Kidney Disease, Abnormal Renal Function, and Gout and Asymptomatic Hyperuricemia.
Categories: Cytochrome P-450 CYP2C19 Inhibitors, Cytochrome P-450 CYP2C9 InhibitorsSynonyms: 2-ethyl-3-(3,5-dibrom-4-hydroxybenzoyl)benzofuran, 3,5-dibromo-4-hydroxyphenyl-2-ethyl-3-benzofuranyl ketoneNabilone
go.drugbank.com/drugs/DB00486ApprovedInvestigationalNabilone is a racemate consisting of the (S,S) and the (R,R) isomers. … Nabilone (marketed as Cesamet) is a synthetic form of delta-9-tetrahydrocannabinol (Δ⁹-THC), the primary psychoactive component of cannabis (marijuana).
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsProducts: Canemes 1 mg KapselnMitotane
go.drugbank.com/drugs/DB00648ApprovedInvestigationalMitotane is an adrenolytic isomer of the insecticide dichlorodiphenyldichloroethane (DDD) - itself a metabolite of dichlorodiphenyltrichloroethane (DDT) - that inhibits cells of the adrenal cortex and
Categories: Cytochrome P-450 CYP3A Inducers, Cytochrome P-450 CYP3A4 InducersSynonyms: 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-benzene, o,p'-DDDOxymetazoline
go.drugbank.com/drugs/DB00935ApprovedInvestigationalOxymetazoline is an imidazole derivative and a potent, direct-acting alpha (α)-adrenergic agonist with affinity to both α<sub>1</sub>- and α<sub>2</sub>-adrenoceptors. … [A215542] Oxymetazoline is available in various formulations with a wide variety of clinical implications. The topical formulation of the drug is used to treat persistent facial redness in adults.
Mixtures: N-S-4Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 SubstratesGilteritinib
go.drugbank.com/drugs/DB12141ApprovedInvestigational[A40036] It is a pyrazinecarboxamide derivative that showed high selectivity to FLT3 preventing the c-Kit -driven myelosuppression observed in other therapies. … Gilteritinib, also known as ASP2215, is a small molecule part of the FLT3 tyrosine kinase inhibitors that presented a greater selectivity and potency when compared with other agents from this group.
Categories: fms-Like Tyrosine Kinase 3, antagonists & inhibitors, Cytochrome P-450 SubstratesProducts: XOSPATA 40 MG FİLM KAPLI TABLET, 84 ADET, XOSPATA® FILM-COATED TABLETS 40MGPoa pratensis pollen
go.drugbank.com/drugs/DB10366ApprovedPoa pratensis pollen is the pollen of the Poa pratensis plant. Poa pratensis pollen is mainly used in allergenic testing.
Mixtures: 7 Grass Mix, 7 Grass MixProducts: Standardized Grass Pollen - Kentucky Bluegrass (100 Bau/ml), Standardized Grass Pollen - Kentucky Bluegrass (100000 Bau/ml)