Identification

Summary

Poa pratensis pollen is an extract from Poa pratensis pollen used in allergy testing.

Brand Names
Oralair 100, Oralair 300, Oralair Children and Adolescents Sample Kit
Generic Name
Poa pratensis pollen
DrugBank Accession Number
DB10366
Background

Poa pratensis pollen is the pollen of the Poa pratensis plant. Poa pratensis pollen is mainly used in allergenic testing.

Type
Biotech
Groups
Approved
Biologic Classification
Allergenics
Allergen Extract
Synonyms
  • Kentucky bluegrass pollen extract
  • Meadowgrass pollen extract
  • Poa pratensis
  • Standardized kentucky blue/june grass pollen

Pharmacology

Indication

Poa pratensis pollen is an allergen extract included in an allergenic testing product called ORALAIR. It is indicated as immunotherapy for the treatment of grass pollen-induced allergic rhinitis with or without conjunctivitis confirmed by positive skin test or in vitro testing for pollen38 specific IgE antibodies for any of the five grass species contained in this product. ORALAIR is approved for use in persons 5 through 65 years of age.1

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Associated Conditions
Contraindications & Blackbox Warnings
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Pharmacodynamics

Not Available

Mechanism of action
Not Available
Absorption

Not Available

Volume of distribution

Not Available

Protein binding

Not Available

Metabolism
Not Available
Route of elimination

Not Available

Half-life

Not Available

Clearance

Not Available

Adverse Effects
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Toxicity

Not Available

Pathways
Not Available
Pharmacogenomic Effects/ADRs
Not Available

Interactions

Drug Interactions
This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.
DrugInteraction
AcebutololThe risk of a hypersensitivity reaction to Poa pratensis pollen is increased when it is combined with Acebutolol.
AtenololThe risk of a hypersensitivity reaction to Poa pratensis pollen is increased when it is combined with Atenolol.
BenazeprilThe risk or severity of adverse effects can be increased when Benazepril is combined with Poa pratensis pollen.
BetaxololThe risk of a hypersensitivity reaction to Poa pratensis pollen is increased when it is combined with Betaxolol.
BisoprololThe risk of a hypersensitivity reaction to Poa pratensis pollen is increased when it is combined with Bisoprolol.
CaptoprilThe risk or severity of adverse effects can be increased when Captopril is combined with Poa pratensis pollen.
CarvedilolThe risk of a hypersensitivity reaction to Poa pratensis pollen is increased when it is combined with Carvedilol.
CeliprololThe risk of a hypersensitivity reaction to Poa pratensis pollen is increased when it is combined with Celiprolol.
CilazaprilThe risk or severity of adverse effects can be increased when Cilazapril is combined with Poa pratensis pollen.
EnalaprilThe risk or severity of adverse effects can be increased when Enalapril is combined with Poa pratensis pollen.
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Food Interactions
Not Available

Products

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Brand Name Prescription Products
NameDosageStrengthRouteLabellerMarketing StartMarketing EndRegionImage
Allergenic Extract - Standardized Grass Pollen - Kentucky Blue/juneLiquid10000 unit / mLIntradermal; SubcutaneousGreer LaboratoriesNot applicableNot applicableCanada flag
Allergenic Extract - Standardized Grass Pollen - Kentucky Blue/juneLiquid100000 unit / mLIntradermal; SubcutaneousGreer Laboratories2000-10-30Not applicableCanada flag
Allergenic Extract - Standardized June Grass PollenLiquid100000 unit / mLIntradermal; Percutaneous; SubcutaneousAlk Abello, Inc.2009-07-30Not applicableCanada flag
Center-AL - Poa Pratensis PollenInjection, suspension20000 [PNU]/1mLSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
Center-AL - Poa Pratensis PollenInjection, suspension10000 [PNU]/1mLSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
Center-AL - Poa Pratensis PollenInjection, suspension20000 [PNU]/1mLSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
Kentucky Bluegrass (June) StandardizedInjection, solution10000 [BAU]/1mLSubcutaneousALK-Abello, Inc.1997-12-18Not applicableUS flag
Kentucky Bluegrass (June) StandardizedSolution10000 [BAU]/1mLPercutaneousALK-Abello, Inc.1997-12-182019-10-17US flag
Kentucky Bluegrass (June) StandardizedInjection, solution100000 [BAU]/1mLSubcutaneousALK-Abello, Inc.1997-12-18Not applicableUS flag
Kentucky Bluegrass (June) StandardizedSolution100000 [BAU]/1mLPercutaneousALK-Abello, Inc.1997-12-18Not applicableUS flag
Mixture Products
NameIngredientsDosageRouteLabellerMarketing StartMarketing EndRegionImage
5 Grass MixPoa pratensis pollen (1000 [PNU]/1mL) + Agrostis gigantea pollen (1000 [PNU]/1mL) + Anthoxanthum odoratum pollen (1000 [PNU]/1mL) + Dactylis glomerata pollen (1000 [PNU]/1mL) + Phleum pratense pollen (1000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
5 Grass MixPoa pratensis pollen (20000 [PNU]/1mL) + Agrostis gigantea pollen (20000 [PNU]/1mL) + Anthoxanthum odoratum (20000 [PNU]/1mL) + Dactylis glomerata pollen (20000 [PNU]/1mL) + Phleum pratense pollen (20000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
5 Grass MixPoa pratensis pollen (10000 [PNU]/1mL) + Agrostis gigantea pollen (10000 [PNU]/1mL) + Anthoxanthum odoratum pollen (10000 [PNU]/1mL) + Dactylis glomerata pollen (10000 [PNU]/1mL) + Phleum pratense pollen (10000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
5 Grass MixPoa pratensis pollen (10000 [PNU]/1mL) + Agrostis gigantea pollen (10000 [PNU]/1mL) + Anthoxanthum odoratum (10000 [PNU]/1mL) + Dactylis glomerata pollen (10000 [PNU]/1mL) + Phleum pratense pollen (10000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
5 Grass MixPoa pratensis pollen (5000 [PNU]/1mL) + Agrostis gigantea pollen (5000 [PNU]/1mL) + Anthoxanthum odoratum pollen (5000 [PNU]/1mL) + Dactylis glomerata pollen (5000 [PNU]/1mL) + Phleum pratense pollen (5000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
5 Grass MixPoa pratensis pollen (100 [PNU]/1mL) + Agrostis gigantea pollen (100 [PNU]/1mL) + Anthoxanthum odoratum pollen (100 [PNU]/1mL) + Dactylis glomerata pollen (100 [PNU]/1mL) + Phleum pratense pollen (100 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
6 Grass MixPoa pratensis pollen (20000 [PNU]/1mL) + Agrostis gigantea pollen (20000 [PNU]/1mL) + Dactylis glomerata pollen (20000 [PNU]/1mL) + Festuca pratensis pollen (20000 [PNU]/1mL) + Lolium perenne pollen (20000 [PNU]/1mL) + Phleum pratense pollen (20000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
6 Grass MixPoa pratensis pollen (10000 [PNU]/1mL) + Agrostis gigantea pollen (10000 [PNU]/1mL) + Dactylis glomerata pollen (10000 [PNU]/1mL) + Festuca pratensis pollen (10000 [PNU]/1mL) + Lolium perenne pollen (10000 [PNU]/1mL) + Phleum pratense pollen (10000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
7 Grass MixPoa pratensis pollen (10000 [PNU]/1mL) + Agrostis gigantea pollen (10000 [PNU]/1mL) + Anthoxanthum odoratum (10000 [PNU]/1mL) + Dactylis glomerata pollen (10000 [PNU]/1mL) + Festuca pratensis pollen (10000 [PNU]/1mL) + Lolium perenne pollen (10000 [PNU]/1mL) + Phleum pratense pollen (10000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag
7 Grass MixPoa pratensis pollen (20000 [PNU]/1mL) + Agrostis gigantea pollen (20000 [PNU]/1mL) + Anthoxanthum odoratum (20000 [PNU]/1mL) + Dactylis glomerata pollen (20000 [PNU]/1mL) + Festuca pratensis pollen (20000 [PNU]/1mL) + Lolium perenne pollen (20000 [PNU]/1mL) + Phleum pratense pollen (20000 [PNU]/1mL)Injection, solutionSubcutaneousALK-Abello, Inc.1975-01-15Not applicableUS flag

Categories

Drug Categories
Classification
Not classified
Affected organisms
Not Available

Chemical Identifiers

UNII
ZO990O27NP
CAS number
Not Available

References

General References
  1. FDA Approved Drug Products: ORALAIR 6 (Sweet Vernal, Orchard, Perennial Rye, Timothy, and Kentucky Blue Grass Mixed Pollens Allergen Extract) Tablet for Sublingual Use [Link]
PubChem Substance
347910543
RxNav
852834

Clinical Trials

Clinical Trials
PhaseStatusPurposeConditionsCount
3Active Not RecruitingTreatmentAllergic Reaction1
Not AvailableCompletedNot AvailableAllergic Reaction1

Pharmacoeconomics

Manufacturers
Not Available
Packagers
Not Available
Dosage Forms
FormRouteStrength
SolutionIntradermal; Percutaneous; Subcutaneous
Injection, solutionSubcutaneous
LiquidIntradermal; Percutaneous; Subcutaneous
LiquidIntradermal; Subcutaneous10000 unit / mL
LiquidIntradermal; Subcutaneous100000 unit / mL
LiquidIntradermal; Percutaneous; Subcutaneous100000 unit / mL
LiquidSubcutaneous
SolutionIntradermal; Subcutaneous
Injection, suspensionSubcutaneous10000 [PNU]/1mL
Injection, suspensionSubcutaneous20000 [PNU]/1mL
Injection, solutionPercutaneous
Injection, solutionSubcutaneous10000 [BAU]/1mL
Injection, solutionSubcutaneous100000 [BAU]/1mL
SolutionPercutaneous10000 [BAU]/1mL
SolutionPercutaneous100000 [BAU]/1mL
KitSublingual
TabletSublingual
TabletSublingual100 [IR]
TabletSublingual300 [IR]
Tablet, orally disintegratingSublingual
LiquidIntradermal100 unit / mL
LiquidIntradermal1000 unit / mL
SolutionPercutaneous; Subcutaneous10000 unit / mL
SolutionPercutaneous; Subcutaneous100000 unit / mL
Injection, solutionIntradermal100 [BAU]/1mL
Injection, solutionIntradermal1000 [BAU]/1mL
Injection, solutionPercutaneous; Subcutaneous10000 [BAU]/1mL
Injection, solutionIntradermal
Injection, solutionPercutaneous; Subcutaneous
Injection, solutionIntradermal; Subcutaneous10000 [BAU]/1mL
Injection, solutionIntradermal; Subcutaneous100000 [BAU]/1mL
SolutionIntradermal; Percutaneous; Subcutaneous10000 [BAU]/1mL
SolutionIntradermal; Percutaneous; Subcutaneous100000 [BAU]/1mL
InjectionCutaneous; Intradermal; Subcutaneous100000 [BAU]/1mL
Injection, solutionPercutaneous; Subcutaneous100000 [BAU]/1mL
Injection, solutionIntradermal; Subcutaneous
Prices
Not Available
Patents
Not Available

Properties

State
Not Available
Experimental Properties
Not Available

Drug created at December 01, 2015 20:03 / Updated at June 28, 2022 06:16