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Displaying results 3471 - 3480 of 9129 in total
  1. Drug

    Alinidine

    go.drugbank.com/drugs/DB20618
    Experimental

    Alinidine is a small molecule drug. The usage of the INN stem '-nidine' in the name indicates that Alinidine is a a2 adrenoreceptor agonist. Alinidine has a monoisotopic molecular weight of 269.05 Da.

    Synonyms: St 567 br (as hbr)
  2. Drug

    Goxalapladib

    go.drugbank.com/drugs/DB20736
    Experimental

    Goxalapladib is a small molecule drug. The usage of the INN stem '-pladib' in the name indicates that Goxalapladib is a phospholipase A2​ inhibitor. … Goxalapladib has a monoisotopic molecular weight of 718.29 Da.

  3. Drug

    Indanidine

    go.drugbank.com/drugs/DB20950
    Experimental

    Indanidine is a small molecule drug. The usage of the INN stem '-nidine' in the name indicates that Indanidine is a a2 adrenoreceptor agonist. … Indanidine has a monoisotopic molecular weight of 215.12 Da.

  4. Drug

    Menotropins

    go.drugbank.com/drugs/DB00032
    ApprovedInvestigational

    It is used as a fertility medication that is injected either subcutaneously or intramuscularly.

  5. Drug

    Physostigmine

    go.drugbank.com/drugs/DB00981
    Approved

    A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. … It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity.

  6. Drug

    Anisotropine methylbromide

    go.drugbank.com/drugs/DB00517
    Approved

    Anisotropine methylbromide is a quaternary ammonium compound. Its use as treatment adjunct in peptic ulcer has been replaced by the use of more effective agents. … Depending on the dose, anisotropine methylbromide may reduce the motility and secretory activity of the gastrointestinal system, and the tone of the ureter and urinary bladder and may have a slight relaxant

  7. Drug

    Isavuconazonium

    go.drugbank.com/drugs/DB06636
    ApprovedInvestigational

    Isovuconazonium has excellent oral bioavailability, predictable pharmacokinetics, and a good safety profile, making it a reasonable alternative to its few other competitors on the market. … This formulation also avoids the use of a cyclodextrin vehicle for solubilization required for intravenous administration of other antifungals such as voriconazole and posaconazole, eliminating concerns

  8. Drug

    Tovorafenib

    go.drugbank.com/drugs/DB15266
    ApprovedInvestigational

    Tovorafenib is a selective type II RAF kinase inhibitor with anti-tumour activity. … [A263597] It was granted accelerated approval by the FDA, making it the first FDA approval of a systemic therapy for the treatment of pediatric low-grade glioma, with BRAF rearrangements.

  9. Drug

    Borage oil

    go.drugbank.com/drugs/DB11238
    Approved

    Borage oil is used as an herbal treatment of skin disorders including eczema, seborrheic dermatitis, and neurodermatitis as well as other inflammatory, cardiovascular and endocrine disorders, although … GLA, which accounts for approximately 24% of the oil, is converted to dihomo-γ-linolenic acid (DGLA) which acts as a precursor to anti-inflammatory mediators such as 1-series prostaglandins and the 3-series

  10. Drug

    Alclometasone

    go.drugbank.com/drugs/DB00240
    Approved

    Alclometasone is synthetic glucocorticoid steroid for topical use in dermatology as anti-inflammatory, antipruritic, antiallergic, antiproliferative and vasoconstrictive agent.