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Displaying results 3481 - 3490 of 10000 in total
  1. Target

    5'(3')-deoxyribonucleotidase, mitochondrial

    go.drugbank.com/bio_entities/BE0001515
    TargetHumans

    Dephosphorylates preferentially the 5'- and 2'(3')-phosphates of uracil and thymine (deoxy)ribonucleotide monophosphates (PubMed:10899995, PubMed:16004879).

    Polypeptides: 5'(3')-deoxyribonucleotidase, mitochondrialSynonyms: Deoxy-5'-nucleotidase 2, 5',3'-nucleotidase, mitochondrial
  2. Target

    5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

    go.drugbank.com/bio_entities/BE0001620
    TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)

    Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.

    Polypeptides: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferaseFunction: 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity
  3. Target

    Orotidine 5'-phosphate decarboxylase

    go.drugbank.com/bio_entities/BE0001677
    TargetEnzymeEscherichia coli (strain K12)

    Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

    Polypeptides: Orotidine 5'-phosphate decarboxylase
  4. Target

    Orotidine 5'-phosphate decarboxylase

    go.drugbank.com/bio_entities/BE0001956
    TargetBacillus subtilis (strain 168)

    Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).

    Polypeptides: Orotidine 5'-phosphate decarboxylaseFunction: orotidine-5'-phosphate decarboxylase activity
  5. Target

    Inosine-5'-monophosphate dehydrogenase

    go.drugbank.com/bio_entities/BE0002047
    TargetStreptococcus pyogenes

    Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays

    Polypeptides: Inosine-5'-monophosphate dehydrogenase
  6. Target

    Laminin subunit alpha-5

    go.drugbank.com/bio_entities/BE0002103
    TargetHumans

    Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Plays a...

    Polypeptides: Laminin subunit alpha-5Synonyms: Laminin-15 subunit alpha
  7. Target

    Somatostatin receptor type 5

    go.drugbank.com/bio_entities/BE0002147
    TargetHumans

    Receptor for somatostatin 28 and to a lesser extent for somatostatin-14. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Increases cell growth inhibition activity of SSTR2 following heterodimerization

    Polypeptides: Somatostatin receptor type 5Synonyms: SS-5-R
  8. Target

    Pyrroline-5-carboxylate reductase

    go.drugbank.com/bio_entities/BE0002335
    TargetHumans

    Polypeptides: Pyrroline-5-carboxylate reductaseFunction: pyrroline-5-carboxylate reductase activity
  9. Target

    Deoxyuridine 5'-triphosphate nucleotidohydrolase

    go.drugbank.com/bio_entities/BE0003348
    TargetPlasmodium falciparum (isolate 3D7)

    Involved in nucleotide metabolism via production of dUMP, the immediate precursor of thymidine nucleotides, and decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.

    Polypeptides: Deoxyuridine 5'-triphosphate nucleotidohydrolaseSynonyms: Deoxyuridine 5'-triphosphate nucleotidohydrolase, putative
  10. Target

    Nuclear receptor coactivator 5

    go.drugbank.com/bio_entities/BE0004057
    TargetHumans

    Nuclear receptor coregulator that can have both coactivator and corepressor functions. Interacts with nuclear receptors for steroids (ESR1 and ESR2) independently of the steroid binding domain (AF-2) of the ESR receptors, and with the or...

    Polypeptides: Nuclear receptor coactivator 5Synonyms: NCoA-5