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Displaying results 3521 - 3530 of 7284 in total
  1. Drug

    Uplarafenib

    go.drugbank.com/drugs/DB21661
    Experimental

    Uplarafenib has a monoisotopic molecular weight of 494.12 Da. … Uplarafenib is a small molecule drug. The usage of the INN stem '-rafenib' in the name indicates that Uplarafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor.

  2. Drug

    Fosrolapitant

    go.drugbank.com/drugs/DB21723
    Investigational

    Fosrolapitant has a monoisotopic molecular weight of 654.16 Da. … Fosrolapitant is a small molecule drug. The usage of the INN stem '-pitant' in the name indicates that Fosrolapitant is a neurokinin NK1​ (substance P) receptor antagonist.

  3. Drug

    Flezurafenib

    go.drugbank.com/drugs/DB21725
    Experimental

    Flezurafenib has a monoisotopic molecular weight of 456.16 Da. … Flezurafenib is a small molecule drug. The usage of the INN stem '-rafenib' in the name indicates that Flezurafenib is a Raf (rapidly accelerated fibrosarcoma) kinase inhibitor.

  4. Target

    NF-kappa-B inhibitor alpha

    go.drugbank.com/bio_entities/BE0003469
    TargetHumans

    Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL (RELA/p65 and NFKB1/p50) dimers in the cytoplasm by masking their nuclear localization signals (PubMed:1493333, PubMed:36651806, PubMed:7479976). On cellular stimu...

    Synonyms: Major histocompatibility complex enhancer-binding protein MAD3
  5. Drug

    YKP-1358

    go.drugbank.com/drugs/DB06109
    Experimental

    YKP1358 is a novel serotonin (5-HT2A) and dopamine (D2) antagonist that has demonstrated potent activity in animals that relates to both positive and negative symptoms of schizophrenia. … In addition, the YKP1358 pharmacological profile suggests a very low potential for extrapyramidal side effects.

    Categories: Dopamine D2 Receptor Antagonists
  6. Drug

    Ribuvaptan

    go.drugbank.com/drugs/DB20059
    Experimental

    Ribuvaptan has a monoisotopic molecular weight of 595.11 Da. … Ribuvaptan is a small molecule drug. The usage of the INN stem '-vaptan' in the name indicates that Ribuvaptan is a vasopressin receptor antagonist.

  7. Drug

    Fasobegron

    go.drugbank.com/drugs/DB20200
    Experimental

    Fasobegron has a monoisotopic molecular weight of 425.14 Da. … Fasobegron is a small molecule drug. The usage of the INN stem '-begron' in the name indicates that Fasobegron is a β3​ adrenoreceptor agonists.

  8. Drug

    Ruclosporin

    go.drugbank.com/drugs/DB21199
    Experimental

    Ruclosporin has a monoisotopic molecular weight of 1330.92 Da. … Ruclosporin is a small molecule drug. The usage of the INN stem '-(clo)sporin' in the name indicates that Ruclosporin is a cyclosporine derivative.

  9. Drug

    Filapixant

    go.drugbank.com/drugs/DB21467
    Experimental

    Filapixant has a monoisotopic molecular weight of 521.17 Da. … Filapixant is a small molecule drug. The usage of the INN stem '-pixant' in the name indicates that Filapixant is a purinoreceptor (P2X) antagonist.

  10. Drug

    Teplinovivint

    go.drugbank.com/drugs/DB21475
    Experimental

    Teplinovivint has a monoisotopic molecular weight of 442.21 Da. … Teplinovivint is a small molecule drug. The usage of the INN stem '-vivint' in the name indicates that Teplinovivint is a Wnt signaling inhibitor.