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Displaying results 3541 - 3550 of 10000 in total
  1. Target

    Serotonin Receptors

    go.drugbank.com/bio_entities/BE0004862
    TargetHumans

    Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects … Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons

    Polypeptides: 5-hydroxytryptamine receptor 1A, 5-hydroxytryptamine receptor 1BSynonyms: 5-HT1A, 5-HT-1A
  2. Drug

    Vespula vulgaris venom protein

    go.drugbank.com/drugs/DB11033
    Approved

    Vespula vulgaris venom protein is an extract of Vespula vulgaris venom. Vespula vulgaris venom protein is used in allergenic testing.

    Mixtures: Mixed Vespid Venom Protein Multidose 13.0 Ml (3900 Mcg), Hymenoptera Venom Product-mixed Vespid Venom Protein (1650 Mcg)Products: ALUTARD SQ Wespengift Injektionssuspension (Anfangsbehandlung) (100 SQ E/ml, 1.000 SQ E/ml, 10.000 SQ E/ml und 100.000 SQ E/ml), ALUTARD SQ Wespengift 100.000 SQ-E/ml Injektionssuspension (Fortsetzungsbehandlung)
  3. Drug

    Brexpiprazole

    go.drugbank.com/drugs/DB09128
    ApprovedInvestigational

    It also displays stronger antagonism at the 5-HT1A and 5-HT2A receptors.[A182186, A38385, A259661] Brexpiprazole was first approved by the FDA on July 10, 2015. … Brexpiprazole is an atypical antipsychotic and a novel D2 dopamine and serotonin 1A partial agonist called serotonin-dopamine activity modulator (SDAM).

    Categories: Serotonin 5-HT1 Receptor Agonists, Serotonin 5-HT2 Receptor AntagonistsProducts: REXULTI (BREXPIPRAZOLE) TABLETS 1 MG, REXULTI (BREXPIPRAZOLE) TABLETS 2 MG
  4. Drug

    Canagliflozin

    go.drugbank.com/drugs/DB08907
    ApprovedInvestigational

    Canagliflozin, also known as _Invokana_, is a sodium-glucose cotransporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus along with lifestyle changes including diet and exercise … It was initially approved by the FDA in 2013 for the management of diabetes and later approved in 2018 for a second indication of reducing the risk of cardiovascular events in patients diagnosed with type

    Mixtures: VOKANAMET 50 MG/500 MG, FILM-COATED TABLETS 50 MG / 1000 MGCategories: Drugs Used in Diabetes, Cytochrome P-450 Substrates
  5. Drug

    Amphetamine

    go.drugbank.com/drugs/DB00182
    ApprovedIllicitInvestigational

    This use derived into a large overproduction of amphetamine and all the surplus after the war finalized ended up in the black market, producing the initiation of the illicit abuse.[A18540] … Amphetamine, a compound discovered over 100 years ago, is one of the more restricted controlled drugs.

    Mixtures: Mixed Salts of a Single-Entity Amphetamine Product, Mixed Salts of a Single-Entity Amphetamine ProductCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 Inhibitors
  6. Pathway

    5-Oxoprolinase Deficiency

    smpdb.ca/view/SMP0000500
    Disease

    5-Oxoprolinase deficiency, also called OPLAHD, is a rare inborn error of metabolism (IEM) and autosomal recessive disorder of glutathione metabolism caused by a defective 5-oxoprolinase. 5-Oxoprolinase … This disorder is characterized by a large accumulation of 5-oxoproline in the urine.

    Drugs: Glutamic acid · Glutathione · Glycine · Cysteine · Alanine · ATP +5 more
    Enzymes: 5-oxoprolinase
  7. Pathway

    Acylcarnitine 5-octenoylcarnitine

    smpdb.ca/view/SMP0123372
    Metabolic

    5-octenoylcarnitine is an acylcarnitine. … Once in the matrix, 5-octenoylcarnitine can react with the carnitine O-palmitoyltransferase 2 enzyme found in the mitochondrial inner membrane to once again form 5-octenoyl-CoA and L-carnitine. 5-octenoyl-CoA

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  8. Pathway

    Acylcarnitine 5-Methylnonanoylcarnitine

    smpdb.ca/view/SMP0123580
    Metabolic

    5-Methylnonanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-methylnonanoyl-CoA reacts with L-carnitine to form 5-methylnonanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  9. Pathway

    Acylcarnitine 5-Methyldecanoylcarnitine

    smpdb.ca/view/SMP0123589
    Metabolic

    5-Methyldecanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-methyldecanoyl-CoA reacts with L-carnitine to form 5-methyldecanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5
  10. Pathway

    Acylcarnitine 5-Methyltetradecanoylcarnitine

    smpdb.ca/view/SMP0123633
    Metabolic

    5-Methyltetradecanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, 5-methyltetradecanoyl-CoA reacts with L-carnitine to form 5-methyltetradecanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.

    Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 more
    Enzymes: Solute carrier family 22 member 5