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Chloramphenicol succinate
go.drugbank.com/drugs/DB07565ApprovedChloramphenicol succinate is an ester prodrug of [chloramphenicol].[A192987] Chloramphenicol is a bacteriostatic antibiotic. … [L14174] Chloramphenicol succinate was granted FDA approval on 20 February 1959.[L12711]
Categories: P-glycoprotein substrates with a Narrow Therapeutic IndexPiperaquine
go.drugbank.com/drugs/DB13941ApprovedInvestigationalPiperaquine is an antimalarial agent first synthesized in the 1960's and used throughout China [A31550]. … It has come back into use in combination with the artemisinin derivative [DB11638] as part of the combination product Eurartesim [FDA Label].
Mixtures: D-ARTEPP, D-ARTEPP DISPERSIBLEMasoprocol
go.drugbank.com/drugs/DB00179InvestigationalThe compound also inhibits formyltetrahydrofolate synthetase, carboxylesterase, and cyclooxygenase to a lesser extent. It also serves as an antioxidant in fats and oils. [PubChem] … A potent lipoxygenase inhibitor that interferes with arachidonic acid metabolism.
Categories: Compounds used in a research, industrial, or household settingLefamulin
go.drugbank.com/drugs/DB12825Approved[A183206] Lefamulin is available in intravenous and oral preparations and was granted FDA approval in August 2019. … A pleuromotilin is a more recently developed type of antibiotic that is derived from the fungus, Pleurotus mutilus.
Alifedrine
go.drugbank.com/drugs/DB20853ExperimentalAlifedrine is a small molecule drug. The usage of the INN stem '-drine' in the name indicates that Alifedrine is a sympathomimetic. Alifedrine has a monoisotopic molecular weight of 289.2 Da.
Categories: Compounds used in a research, industrial, or household settingBrotizolam
go.drugbank.com/drugs/DB09017ApprovedWithdrawnBrotizolam is a sedative-hypnotic thienodiazepine drug which is a benzodiazepine analog. It demonstrates anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant effects. … Brotizolam is not approved for sale in the UK, United States or Canada but is sold in the Netherlands, Germany, Spain, Belgium, Austria, Portugal, Israel, Italy and Japan.
Oxiconazole
go.drugbank.com/drugs/DB00239ApprovedOxiconazole is an antifungal agent that is commonly found in topical formulations. … It is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin infections such as athlete's foot, jock itch and ringworm.
Rofecoxib
go.drugbank.com/drugs/DB00533ApprovedWithdrawnRofecoxib is a solid. This compound belongs to the stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. … Rofecoxib is used for the treatment of osteoarthritis, rheumatoid arthritis, acute pain in adults, and primary dysmenorrhea, as well as acute treatment of migraine attacks with or without auras.
Toluene
go.drugbank.com/drugs/DB11558InvestigationalVet approvedToluene is a colorless, liquid that is immiscible in water. It is a mono-substituted benzene derivative used in veterinary medicine as a treatment for various parasites in dogs and cats.
Categories: Compounds used in a research, industrial, or household settingNalidixic acid
go.drugbank.com/drugs/DB00779ApprovedWithdrawnNalidixic acid is a synthetic 1,8-naphthyridine antimicrobial agent with a limited bacteriocidal spectrum. It is an inhibitor of the A subunit of bacterial DNA gyrase.
Synonyms: 1-Aethyl-7-methyl-1,8-naphthyridin-4-on-3-karbonsaeureInternational brands: Huei Yi