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Displaying results 3561 - 3570 of 10000 in total
  1. Drug

    Prednicarbate

    go.drugbank.com/drugs/DB01130
    Approved

    IL-1a is also found in fibroblasts, where it is responsible for proliferation, collagenase induction and IL-6 synthesis, which are related to skin thickness. … The anti-inflammation action of corticosteroids is associated with the inhibition of the interleukin 1-alpha cytokine within keratinocytes.

    Mixtures: SKINPRED® ULTRACategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A Inducers
  2. Drug

    Cendakimab

    go.drugbank.com/drugs/DB18427
    Investigational

    Cendakimab is a recombinant humanized anti-interleukin 13 (IL-13) monoclonal antibody.

    Synonyms: )) (10.7.15) (1-123) -HOMO SAPIENS IGHG1*03V, G1M3>G, IMMUNOGLOBULIN G1(240-ALANINE, 241-ALANINE), ANTI-(HUMAN INTERLEUKIN 13) (HUMAN-MUS MUSCULUS MONOCLONAL RPC4046 .GAMMA.-1), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL RPC4046 .KAPPA.-1, DIMER
  3. Drug

    Dirithromycin

    go.drugbank.com/drugs/DB00954
    Investigational

    Dirithromycin is a macrolide glycopeptide antibiotic used to treat many different types of bacterial infections, such as bronchitis, pneumonia, tonsillitis, and even skin infections.

    Synonyms: (9S)-9-deoxo-11-deoxy-9,11-(imino((1R)-2-(2-methoxyethoxy)ethylidene)oxy)erythromycinCategories: Cytochrome P-450 CYP3A Inhibitors, Cytochrome P-450 CYP3A4 Inhibitors
  4. Drug

    Edotreotide gallium Ga-68

    go.drugbank.com/drugs/DB15494
    Approved

    [A185852] Edotreotide gallium Ga-68 was granted FDA approval on 21 August 2019.[L8597] … Edotreotide gallium Ga-68 is an 8 amino acid peptide bound to the chelator 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA).

    Products: Sogacin 20 MBq/ml Injektionslösung
  5. Drug

    Valbenazine

    go.drugbank.com/drugs/DB11915
    ApprovedInvestigational

    The reduction in chorea severity was observed as early as 2 weeks after starting treatment with an initial dose of 40 mg.[L47910] … Valbenazine is a modified metabolite of [tetrabenazine], and it is currently being approved for the treatment of various movement disorders, particularly tardive dyskinesia and chorea associated with Huntington's

    Categories: Heterocyclic Compounds, 2-Ring, Vesicular Monoamine Transporter 2 InhibitorProducts: REMLEAS HARD CAPSULES 40 MG, REMLEAS™ hard capsules 40mg
  6. Drug

    Octenidine

    go.drugbank.com/drugs/DB12624
    Investigational

    Octenidine is under investigation in clinical trial NCT02697162 (Antiseptic-coated Intermittent Urinary Catheter).

    Mixtures: Linola sept 1 mg/g + 10 mg/g Wund-Gel, Linola sept 1 mg/g + 20 mg/g Wund-Spray zur Anwendung auf der Haut, LösungCategories: Heterocyclic Compounds, 1-Ring
  7. Drug

    Ganciclovir

    go.drugbank.com/drugs/DB01004
    ApprovedInvestigational

    An acyclovir analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.

    Categories: MATE 1 Substrates, MATE 2 SubstratesSynonyms: 2-amino-9-(2-hydroxy-1-hydroxymethylethoxymethyl)-6,9-dihydro-1H-6-purinone, 2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-1H-purin-6(9H)-one
  8. Target

    3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase

    go.drugbank.com/bio_entities/BE0001679
    TargetMycobacterium tuberculosis

    Probably involved in steroid metabolism. Catalyzes the oxidation of androsterone (3alpha-hydroxy-5alpha-androstan-17-one) and 20beta-hydroxyprogesterone (4-pregnen-20beta-ol-3-one), and the reduction of progesterone (4-pregnen-3,20-dione...

    Polypeptides: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase
  9. Target

    tRNA-dihydrouridine(20) synthase [NAD(P)+]-like

    go.drugbank.com/bio_entities/BE0020091
    EnzymeHumans

    Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs (PubMed:15994936, PubMed:26429968, PubMed:30149704, PubMed:34798057, PubMed:38680565). Specifically modifies U20 in cytoplasmic ...

    Polypeptides: tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
  10. Drug

    Tolfenamic acid

    go.drugbank.com/drugs/DB09216
    Approved

    Tolfenamic acid, with the formula N-(2-methyl-3-chlorphenyl)-anthranilic acid, is a nonsteroidal anti-inflammatory agent. … [A31824] It was discovered by scientists at Medica Pharmaceutical Company in Finland. It is used in the UK as a treatment for migraine under the name of Clotam.

    Categories: Non COX-2 selective NSAIDS, Cytochrome P-450 SubstratesProducts: TOLFEDINE TABLET 60 MG, TOLFEDINE TABLETS 6 MG