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Dual specificity protein phosphatase 5
go.drugbank.com/bio_entities/BE0010466TargetHumansDual specificity protein phosphatase; active with phosphotyrosine, phosphoserine and phosphothreonine residues. The highest relative activity is toward ERK1
Polypeptides: Dual specificity protein phosphatase 5Transcriptional enhancer factor TEF-5
go.drugbank.com/bio_entities/BE0018748TargetHumansTranscription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a ki...
Polypeptides: Transcriptional enhancer factor TEF-5Ribitol 5-phosphate transferase FKRP
go.drugbank.com/bio_entities/BE0019722TargetHumansCatalyzes the transfer of a ribitol 5-phosphate from CDP-L-ribitol to the ribitol 5-phosphate previously attached by FKTN/fukutin to the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta … This constitutes the second step in the formation of the ribose 5-phosphate tandem repeat which links the phosphorylated O-mannosyl trisaccharide to the ligand binding moiety composed of repeats of 3-xylosyl-alpha
Polypeptides: Ribitol 5-phosphate transferase FKRPSynonyms: Ribitol-5-phosphate transferaseEletriptan
go.drugbank.com/drugs/DB00216ApprovedInvestigationalEletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.
Categories: Serotonin-1b and Serotonin-1d Receptor Agonist, Serotonin 5-HT1 Receptor AgonistsProducts: RELPAX 40 MG FILM TABLET, 1 ADET, RELPAX 40 MG FILM TABLET, 2 ADETPeanut
go.drugbank.com/drugs/DB10553ApprovedPeanut allergenic extract is used in allergenic testing.
Mixtures: PALFORZIA (Level 10), PALFORZIA (Level 10)Products: PALFORZIA (Level 5), PALFORZIA (Level 1)Eliglustat
go.drugbank.com/drugs/DB09039ApprovedInvestigationalEliglustat is a glucosylceramide synthase inhibitor used for the long-term treatment of type 1 Gaucher disease. … [A3752,L41404] Gaucher disease is a rare genetic disorder characterized by the deficiency of acid β-glucosidase, an enzyme that converts glucosylceramide into glucose and ceramide.
Categories: Heterocyclic Compounds, 1-Ring, Alimentary Tract and MetabolismSynonyms: N-[(1R,2R)-1-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-hydroxy-3-(1-pyrrolidinyl)-2-propanyl]octanamideTrabectedin
go.drugbank.com/drugs/DB05109ApprovedInvestigationalTrabectedin has a unique mechanism of action. It binds to the minor groove of DNA interfering with cell division and genetic transcription processes and DNA repair machinery. … Trabectedin, also referred as ET-743 during its development, is a marine-derived antitumor agent discovered in the Carribean tunicate _Ecteinascidia turbinata_ and now produced synthetically.
Categories: Heterocyclic Compounds, 1-Ring, Antineoplastic and Immunomodulating AgentsProducts: Yolisar 1 mg I.V. İnfüzyonluk Çözelti Hazırlamada Kullanılacak Konsantre İçin Toz, 1 ADET, YONDELIS 1 MG IV KONSANTRE INFUZYONLUK COZELTI ICIN TOZNADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial
go.drugbank.com/bio_entities/BE0000081TargetHumansAccessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The ...
Polypeptides: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrialSolute carrier family 2, facilitated glucose transporter member 10
go.drugbank.com/bio_entities/BE0005220TransporterHumansFacilitative glucose transporter required for the development of the cardiovascular system
Polypeptides: Solute carrier family 2, facilitated glucose transporter member 10Synonyms: GLUT-10, Glucose transporter type 10Agomelatine
go.drugbank.com/drugs/DB06594ApprovedInvestigationalAgomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression. … Agomelatine was developed in Europe by Servier Laboratories Ltd. and submitted to the European Medicines Agency (EMA) in 2005.
Categories: Serotonin 5-HT2 Receptor Antagonists, Serotonin 5-HT2C Receptor AntagonistsProducts: VALDOXAN 25 MG, VALDOXAN® 25 MG