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Fenfluramine
go.drugbank.com/drugs/DB00574ApprovedIllicitInvestigationalWithdrawnDravet syndrome is a pediatric encephalopathy that typically manifests within the first year of life following exposure to elevated temperatures. … [A214694, A214709, A214712, A214715] Fenfluramine is a serotonergic phenethylamine originally used as an appetite suppressant until concerns regarding cardiotoxicity in obese patients lead to its withdrawal
Synonyms: DL-FenfluramineInternational brands: Ponderax PALoteprednol etabonate
go.drugbank.com/drugs/DB14596ApprovedLoteprednol Etabonate (LE) is a topical corticoid anti-inflammatory. … Moreover, LE was purposefully engineered to be a 'soft drug', one that is designed to be active locally at the site of administration and then rapidly metabolized to inactive components after eliciting
Fidexaban
go.drugbank.com/drugs/DB19562ExperimentalFidexaban has a monoisotopic molecular weight of 526.18 Da. … Fidexaban is a small molecule drug. The usage of the INN stem '-xaban' in the name indicates that Fidexaban is a blood coagulation factor XA inhibitor, antithrombotic.
Cocoa butter
go.drugbank.com/drugs/DB11086ApprovedDyslipidemia is characterized by elevated levels of plasma triglyceride and very-low-density lipoprotein (VLDL) cholesterol due to overproduction of large triglyceride-enriched VLDL cholesterol particles … Still, it is a common active ingredient for prevention of skin dryness in cosmetic and skincare products.
Vitex agnus-castus fruit extract
go.drugbank.com/drugs/DB13193Investigationalmain mechanism of action of vitex agnus-castus fruit extract has not been fully elucidated, however it is suggested to modulate the stress-induced prolactin secretion via dopaminergic actions, and μ (mu
Horse chestnut
go.drugbank.com/drugs/DB13195InvestigationalUnprocessed horse chestnut seeds contain a toxin called esculin (also spelled aesculin) that increases the risk of bleeding due to anticoagulant actions. … Horse chestnut is a flowering plant commonly referred to as *Aesculus hippocastanum*.
Darexaban
go.drugbank.com/drugs/DB12289InvestigationalDarexaban has been used in trials studying the prevention and basic science of Japanese, Caucasian, Thromboembolism, Pharmacodynamics, and Pharmacokinetics, among others.
Categories: Factor Xa InhibitorsBromodiphenhydramine
go.drugbank.com/drugs/DB01237ApprovedBromodiphenhydramine is an ethanolamine antihistamine with antimicrobial property. Bromodiphenhydramine is used in the control of cutaneous allergies. Ethanolamine antihistamines produce marked sedation in most patients.
Pimavanserin
go.drugbank.com/drugs/DB05316ApprovedInvestigationalIn fact, pimavanserin is the first antipsychotic drug without D<sub>2</sub> blocking activity. … [L48236] Although the exact mechanism of action is unknown, it is thought that pimavanserin interacts with the serotonin receptors, particularly the 5-HT<sub>2A</sub> and HT<sub>2C</sub> receptors.