Search
Mirdametinib
go.drugbank.com/drugs/DB07101ApprovedInvestigational[L52485] NF1 is an autosomal-dominant genetic condition caused by loss-of-function variants in the _NF1_ tumour suppressor gene,[A265065,A265070] leading to neurofibromin dysfunction and aberrant activation … Mirdametinib is a mitogen-activated protein kinase (MAP2K, MEK, MAPKK) inhibitor. On February 11, 2025, mirdametinib was approved by the FDA for the treatment of neurofibromatosis type 1 (NF1).
Synonyms: N-(((R)-2,3-DIHYDROXYPROPYL)OXY)-3,4-DIFLUORO-2-((2-FLUORO-4-IODOPHENYL)AMINO)BENZAMIDE N-((2R)-2,3-DIHYDROXYPROPOXY)-3,4-DIFLUORO-2-(2-FLUORO-4-IODOANILINO)BENZAMIDE, (-)-N-(((R)-2,3-DIHYDROXYPROPYL)OXY)-3,4-DIFLUORO-2-((2-FLUORO-4-IODOPHENYL)AMINO)BENZAMIDECategories: Antineoplastic and Immunomodulating AgentsLutein
go.drugbank.com/drugs/DB00137ApprovedNutraceuticalLutein is synthesized only by plants and like other xanthophylls is found in high quantities in green leafy vegetables such as spinach, kale and yellow carrots. … Lutein is an xanthophyll and one of 600 known naturally occurring carotenoids.
Oritavancin
go.drugbank.com/drugs/DB04911ApprovedInvestigational[L12858] Oritavancin was initially approved by the FDA in 2014 and formulated to combat susceptible gram-positive bacteria that cause skin and skin structure infections. … Marketed by Melinta Therapeutics, Kimyrsa offers effective and time-efficient treatment for skin and skin structure infections.[L32629]
Categories: Amino Acids, Peptides, and ProteinsDeep Vein Thrombosis
go.drugbank.com/conditions/DBCOND0029964Drugs: Apixaban · Certoparin · Dabigatran etexilate · Dalteparin · Dermatan sulfate · Desirudin +9 moreSynonyms: Acute embolism and thrombosis of unspecified deep veins of lower extremity, (Deep vein phlebitis and thrombophlebitis of the leg) or (deep vein thrombosis)Padeliporfin
go.drugbank.com/drugs/DB15575ApprovedInvestigational[A244699] Padeliporfin was first approved by the European Commission on November 10, 2017, for the treatment of low-risk prostate cancer in adults meeting certain clinical criteria.[L39799] … Padeliporfin is a water-soluble chlorophyll derivative and cytotoxic photosensitizer used for vascular-targeted photodynamic therapy for malignancies.
Categories: Sensitizers Used in Photodynamic/radiation Therapy, Amino Acids, Peptides, and ProteinsAnisotropine methylbromide
go.drugbank.com/drugs/DB00517ApprovedAnisotropine methylbromide is a quaternary ammonium compound. Its use as treatment adjunct in peptic ulcer has been replaced by the use of more effective agents. … In general, smaller doses of anisotropine methylbromide inhibit salivary and bronchial secretions, sweating, and accommodation; cause dilatation of the pupil; and increase the heart rate.
Olaratumab
go.drugbank.com/drugs/DB06043ApprovedInvestigationalStudies show that the treatment of olaratumab in combination with doxorubicin resulted in significant reduction of cancer cell proliferation and tumor growth. … It is composed of two heavy chain molecule fragments and 2 light chain fragments.
Categories: Amino Acids, Peptides, and Proteins, Antineoplastic and Immunomodulating AgentsTasimelteon
go.drugbank.com/drugs/DB09071ApprovedInvestigationalIn blind individuals, a lack of light stimulation causes an extension of the 24-hour circadian cycle and can lead to progressively delayed sleep onset. … Tasimelteon is currently the only drug available for the treatment of N24HSWD and was granted orphan drug status by the FDA in 2010.
Categories: Hypnotics and SedativesSynonyms: N-{[(1R,2R)-2-(2,3-dihydro-1-benzofuran-4-yl)cyclopropyl]methyl}propanamideAllergic Diseases
go.drugbank.com/conditions/DBCOND0110864Drugs: Acetaminophen · Ammonium chloride · Betamethasone phosphate · Brompheniramine · Buclizine · Budesonide +17 moreSynonyms: Other and unspecified allergy, Atopic AND/OR hypersensitivity stateBetula pendula tar oil
go.drugbank.com/drugs/DB11361ApprovedNutraceuticalThis oil is usually obtained by using both hydrodistillation and micro-distillation[A33154] and it is conformed mainly by [DB11143] and [DB11359]. … Betula pendula tar oil is an essential oil found in the buds of the plant with the same name.