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Displaying results 3681 - 3690 of 10000 in total
  1. Drug

    R-30490

    go.drugbank.com/drugs/DB09179
    Experimental

    R-30490 was found to be the most selective agonist for the mu opioid receptor out of all the fentanyl analogues tested, but it has never been introduced for medical use in humans, although the closely … R-30490 is an opioid related to carfentanil used as an animal tranquilizer.

  2. Drug

    Quercus rubra pollen

    go.drugbank.com/drugs/DB10481
    Approved

    Quercus rubra pollen is the pollen of the Quercus rubra plant. Quercus rubra pollen is mainly used in allergenic testing.

    Mixtures: 10 Tree Mix, Eastern 10 Tree Pollen Mix
  3. Drug

    Dicirenone

    go.drugbank.com/drugs/DB20938
    Experimental

    The usage of the INN stem '-renone' in the name indicates that Dicirenone is a mineralocorticoid receptor (MR, MCR, aldosterone receptor) antagonist.

  4. Drug

    Metreleptin

    go.drugbank.com/drugs/DB09046
    ApprovedInvestigational

    [L41315] Metreleptin was approved by Health Canada in January 2024 for the same patient population, in addition to patients with partial lipodystrophy.[L49901] … [L41315] In February 2014, metreleptin was approved by the FDA for the treatment of complications of leptin deficiency, as an adjunct to diet, in patients with congenital generalized or acquired generalized

  5. Indication

    Abnormal Uterine Bleeding

    go.drugbank.com/conditions/DBCOND0039070
    Drugs: Conjugated estrogens · Ethynodiol diacetate · Medroxyprogesterone acetate · Mestranol · Norgestrel · Progesterone
    Synonyms: Bleeding unrelated to menstrual cycle
  6. Drug

    Influenza B virus B/Washington/02/2019 recombinant hemagglutinin antigen

    go.drugbank.com/drugs/DB15702
    ApprovedWithdrawn

    Vaccines provide protection from influenza by exposing the immune system to the virus (or parts of the virus) which stimulates an immunological defence against future exposure to the virus, or "antigen … that it was previously exposed to.

    Mixtures: FluQuadri Quadrivalent Influenza Vaccine, 0.25 ml, FluQuadri Quadrivalent Influenza Vaccine, 0.5 ml
  7. Drug

    Valoctocogene roxaparvovec

    go.drugbank.com/drugs/DB15561
    ApprovedInvestigationalWithdrawn

    [L43282] The expression of hFVIII-SQ is driven by a liver-specific promoter, which enables hepatocytes to produce factor VIII protein and increase the levels of active factor VIII in blood. … [L43292] Hemophilia A treatments such as prophylactic regimens of exogenous factor VIII or [emicizumab] improve the clinical outcomes of patients but do not eliminate breakthrough bleeding.

    Synonyms: DNA (synthetic adeno-associated virus 5 vector BMN 270 human blood-coagulation factor VIII SQ variant-specifying)
  8. Drug

    Trypsin

    go.drugbank.com/drugs/DB11237
    ApprovedInvestigationalVet approved

    This nucleophilic attack is facilitated by the catalytic triad consisting of histidine-57, aspartate-102, and serine-195. … Therapeutic forms of trypsin is obtained from purified extracts of porcine or bovine pancreas and is intended to aid in digestion when administered orally.

  9. Drug

    Aminopterin

    go.drugbank.com/drugs/DB08878
    ApprovedWithdrawn

    Clinicians need to be aware of the characteristic teratologic effects of aminopterin and methotrexate. … In the 1950's its production was discontinued in favor of methotrexate, which is less potent but less toxic. Off label, aminopterin has also been used in the treatment of psoriasis.

  10. Drug

    Troleandomycin

    go.drugbank.com/drugs/DB13179
    Approved

    A macrolide antibiotic that is similar to erythromycin.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C8 InhibitorsInternational brands: Tao