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Y+L amino acid transporter 1
go.drugbank.com/bio_entities/BE0004769TransporterTargetHumansThe transport mechanism is electroneutral and operates with a stoichiometry of 1:1 (By similarity). … Also mediates arginine transport in non-polarized cells, such as monocytes, and is essential for the correct function of these cells (PubMed:15280038, PubMed:31705628).
Polypeptides: Y+L amino acid transporter 1Synonyms: y(+)L-type amino acid transporter 1Sodium- and chloride-dependent betaine transporter
go.drugbank.com/bio_entities/BE0004777TargetTransporterHumansTransporter that mediates cellular uptake of betaine and GABA in a sodium- and chloride-dependent process (PubMed:7589472).
Polypeptides: Sodium- and chloride-dependent betaine transporterSynonyms: Na(+)/Cl(-) betaine/GABA transporterAmino acid transporter heavy chain SLC3A2
go.drugbank.com/bio_entities/BE0012576TransporterHumansActs as a chaperone that facilitates biogenesis and trafficking of functional transporter heterodimers to the plasma membrane. … Forms heterodimers with SLC7 family transporters (SLC7A5, SLC7A6, SLC7A7, SLC7A8, SLC7A10 and SLC7A11), a group of amino-acid antiporters (PubMed:10574970, PubMed:10903140, PubMed:11557028, PubMed:30867591
Polypeptides: Amino acid transporter heavy chain SLC3A2Function: aromatic amino acid transmembrane transporter activityBacitracin transport ATP-binding protein BcrA
go.drugbank.com/bio_entities/BE0009705TransporterBacillus licheniformisPart of the binding-protein-dependent transport system for bacitracin that confer resistance to this antibiotic. Probably responsible for energy coupling to the transport system (By similarity).
Polypeptides: Bacitracin transport ATP-binding protein BcrATrichlormethiazide
go.drugbank.com/drugs/DB01021ApprovedVet approvedA thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p830)
Categories: Membrane Transport Modulators, Genito Urinary System and Sex HormonesBenzthiazide
go.drugbank.com/drugs/DB00562ApprovedBenzthiazide is used to treat hypertension and edema. Like other thiazides, benzthiazide promotes water loss from the body (diuretics). They inhibit Na+/Cl- reabsorption from the distal convoluted tubules in the kidneys. Thiazides also c...
Categories: Genito Urinary System and Sex HormonesComplex Perianal Fistulas
go.drugbank.com/conditions/DBCOND0153889Drugs: DarvadstrocelSynonyms: Complex Perianal Fistulas, Complex Perianal FistulaNeutral amino acid transporter B(0)
go.drugbank.com/bio_entities/BE0000236TargetTransporterHumansThe transport cycle is usually pH-independent, with the exception of L-glutamate. … Transports extracellular L-glutamate coupled to the cotransport of one proton and one sodium ion in exchange for intracellular L-glutamine counter-ion.
Polypeptides: Neutral amino acid transporter B(0)Synonyms: Sodium-dependent neutral amino acid transporter type 2Ferrichrome outer membrane transporter/phage receptor
go.drugbank.com/bio_entities/BE0001326TargetEscherichia coli (strain K12)Involved in the uptake of iron in complex with ferrichrome, a hydroxamate-type siderophore. Binds and transports ferrichrome-iron across the outer membrane (PubMed:1089064, PubMed:2066336). … In addition to its role in ferrichrome-iron transport, transports the antibiotic albomycin, which is a structural analog of ferrichrome, and acts as a receptor for colicin M, microcin J25 and bacteriophages
Polypeptides: Ferrichrome outer membrane transporter/phage receptorAtomoxetine
go.drugbank.com/drugs/DB00289ApprovedInvestigationalMore recently, positron emission tomography (PET) imaging studies in rhesus monkeys have shown that atomoxetine also binds to the serotonin transporter (SERT),[A178111] and blocks the N-methyl-d-aspartate
Categories: Membrane Transport Modulators