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Midostaurin
go.drugbank.com/drugs/DB06595ApprovedInvestigationalIt was approved on April 28, 2017 and has shown to increase the overall survival rate in patients with AML as an adjunct therapy along with chemotherapeutic agents. … Midostaurin (as Rydapt) is a multitarget kinase inhibitor for the treatment for adult patients with newly diagnosed acute myeloid leukemia (AML) who have a specific genetic mutation called FLT3.
Synonyms: 4'-N-benzoylstaurosporineCategories: Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP1A2 InducersSafinamide
go.drugbank.com/drugs/DB06654ApprovedInvestigationalIt was approved in Europe in February 2015, and in the United States on March 21, 2017.
Categories: Cytochrome P-450 Substrates, Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substratesProducts: Equfina Film coated Tablets 50 mg, XADAGO 50 MG TABLETAS RECUBIERTAS CON PELÍCULARacementhol
go.drugbank.com/drugs/DB14123ApprovedInvestigationalSynonyms: (1R,2S,5R)-Menthol, p-Menthan-3-olMixtures: GR Arthritis pain relief roll-on 1500 mg, JOINT AND MUSCLE RELIEF 450 mgMefloquine
go.drugbank.com/drugs/DB00358ApprovedIndividuals at the highest risk for malaria are those in disease naïve populations, children under age 5, refugees in Central and Eastern Africa, nonimmune civilian and military travelers, pregnant women … Malaria is a protozoan disease that places an enormous burden on human health in endemic areas around the world.
Mixtures: อาร์ทีซูเนทและเมฟลอควินไฮโดรคลอไรด์ 25/55 มก.Categories: P-glycoprotein inhibitors, P-glycoprotein substratesTafamidis
go.drugbank.com/drugs/DB11644ApprovedInvestigational[A189717] Tafamidis was granted an EMA market authorisation on 16 November 2011[L6247] and FDA approval on 3 May 2019.[L11280]
Categories: Heterocyclic Compounds, 2-RingSynonyms: 2-(3,5-Dichlorophenyl)benzoxazole-6-carboxylic acid, 6-BENZOXAZOLECARBOXYLIC ACID, 2-(3,5-DICHLOROPHENYL)-Acylcarnitine (5R)-5-hydroxyhexanoylcarnitine
smpdb.ca/view/SMP0123336Metabolic(5R)-5-hydroxyhexanoylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, (5R)-5-hydroxyhexanoyl-CoA reacts with L-carnitine to form (5R)-5-hydroxyhexanoylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Acylcarnitine Dec-5-enedioylcarnitine
smpdb.ca/view/SMP0123875MetabolicDec-5-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, dec-5-enedioyl-CoA reacts with L-carnitine to form dec-5-enedioylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Acylcarnitine Undec-5-enedioylcarnitine
smpdb.ca/view/SMP0123965MetabolicUndec-5-enedioylcarnitine is an acylcarnitine. … In forming an acylcarnitine derivative, undec-5-enedioyl-CoA reacts with L-carnitine to form undec-5-enedioylcarnitine. This reaction is catalyzed by carnitine O-palmitoyltransferase.
Drugs: Biotin · Adenosine phosphate · ATP · Levocarnitine · Magnesium cation · Pyrophosphoric acid +1 moreEnzymes: Solute carrier family 22 member 5Phosphatidylethanolamine Biosynthesis PE(16:0/20:5(6E,8Z,11Z,14Z,17Z)-OH(5))
smpdb.ca/view/SMP0127207MetabolicPhosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone. They are the second most abundant phospholipid in eukaryotic cell membranes, and contrary to phospha...
Phosphatidylethanolamine Biosynthesis PE(20:5(6E,8Z,11Z,14Z,17Z)-OH(5)/15:0)
smpdb.ca/view/SMP0127519MetabolicPhosphatidylethanolamines (PE) are a class of phospholipids that incorporate a phosphoric acid headgroup into a diacylglycerol backbone. They are the second most abundant phospholipid in eukaryotic cell membranes, and contrary to phospha...