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Inositol nicotinate
go.drugbank.com/drugs/DB08949ApprovedWithdrawnNicotinic acid plays an essential role in many important metabolic processes and has been used as lipid-lowering agent. … It is associated with reduced flushing compared to other vasodilators by being broken down into the metabolites and inositol at a slower rate.
Categories: Nicotinic Acid and DerivativesIsoflavone
go.drugbank.com/drugs/DB12007ApprovedInvestigationalWithdrawnSoybean is an exceptionally rich source of dietary isoflavones, where the average isoflavone content is 1-2 mg/gram [A33103]. … The main soy isoflavones are mostly present in glycosylated forms and include [DB01645], [DB13182], and glycitein, which accounts for approximately 50%, 40%, and 10%, respectively, of the total soybean
Allogenic Donor CD362-enriched Human Umbilical Cord-derived Mesenchymal Stem Cells
go.drugbank.com/drugs/DB15731InvestigationalThe isolated cells are expanded in culture and are able to be used allogenically -- meaning that one donor’s cells can be given to other unrelated patients. … Regarding the modifications of these UC-MSCs, CD362, also known as syndecan-2, is a surface marker identified on MSCs with enhanced clonogenicity and immunomodulatory properties.
Retinol dehydrogenase 12
go.drugbank.com/bio_entities/BE0000726TargetHumansMay play an important function in photoreceptor cells to detoxify 4-hydroxynonenal and potentially other toxic aldehyde products resulting from lipid peroxidation (PubMed:19686838). … Displays high activity towards 9-cis, 11-cis and all-trans-retinal. Shows very weak activity towards 13-cis-retinol (PubMed:12226107, PubMed:15865448).
Synonyms: All-trans and 9-cis retinol dehydrogenaseMyeloid zinc finger 1
go.drugbank.com/bio_entities/BE0013131TargetHumansBinds to target promoter DNA and functions as a transcription regulator. Regulates transcription from the PADI1 and CDH2 promoter.
Synonyms: Zinc finger and SCAN domain-containing protein 6Oxiconazole
go.drugbank.com/drugs/DB00239ApprovedOxiconazole is an antifungal agent that is commonly found in topical formulations. … It is marketed under the brand names Oxistat and Oxistat, and is used in the treatment of various skin infections such as athlete's foot, jock itch and ringworm.
Categories: Imidazole and Triazole Derivatives, Genito Urinary System and Sex HormonesNicergoline
go.drugbank.com/drugs/DB00699ApprovedAn ergot derivative that has been used as a cerebral vasodilator and in peripheral vascular disease. It has been suggested to ameliorate cognitive deficits in cerebrovascular disease.
Categories: Ergot Alkaloids and DerivativesDementia, Multi-Infarct
go.drugbank.com/conditions/DBCOND0006170Drugs: Choline alfoscerateSynonyms: Vascular dementia, unspecified severity, without behavioral disturbance, psychotic disturbance, mood disturbance, and anxietyHeadache, Cluster
go.drugbank.com/conditions/DBCOND0172067Synonyms: Cluster headaches and other trigeminal autonomic cephalgias (TAC)Lymphogranuloma Venereum
go.drugbank.com/conditions/DBCOND0005917Synonyms: Climatic AND/OR tropical bubo