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Amifostine
go.drugbank.com/drugs/DB01143ApprovedInvestigationalA phosphorothioate proposed as a radiation-protective agent. It causes splenic vasodilation and may block autonomic ganglia.
Categories: Compounds used in a research, industrial, or household settingProducts: ETHYOL 500 MG IV INFUZYON ICIN LIYOFIZE TOZ ICEREN FLAKON, 1 ADETWitch hazel
go.drugbank.com/drugs/DB11111ApprovedInvestigationalNutraceuticalMixtures: HAMAZINC KREM ,90 G, HAMAZINC KREM ,30 GProducts: HAMETAN% 25 MERHEM, 50 G, HAMETAN% 25 MERHEM, 30 GCardiolipin Biosynthesis CL(10:0/10:0/20:0/20:0)
smpdb.ca/view/SMP0175544MetabolicCardiolipin (CL) is an important component of the inner mitochondrial membrane where it constitutes about 20% of the total lipid composition.
Tryptophan 5-hydroxylase 1
go.drugbank.com/bio_entities/BE0000121TargetEnzymeHumansOxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis
Polypeptides: Tryptophan 5-hydroxylase 1Synonyms: Tryptophan 5-monooxygenase 1Cytosolic purine 5'-nucleotidase
go.drugbank.com/bio_entities/BE0000261TargetEnzymeHumansBroad specificity cytosolic 5'-nucleotidase that catalyzes the dephosphorylation of 6-hydroxypurine nucleoside 5'-monophosphates (PubMed:10092873, PubMed:12907246, PubMed:1659319, PubMed:9371705).
Polypeptides: Cytosolic purine 5'-nucleotidaseSynonyms: High Km 5'-nucleotidase, Cytosolic 5'-nucleotidase II5'(3')-deoxyribonucleotidase, mitochondrial
go.drugbank.com/bio_entities/BE0001515TargetHumansDephosphorylates preferentially the 5'- and 2'(3')-phosphates of uracil and thymine (deoxy)ribonucleotide monophosphates (PubMed:10899995, PubMed:16004879).
Polypeptides: 5'(3')-deoxyribonucleotidase, mitochondrialSynonyms: Deoxy-5'-nucleotidase 2, 5',3'-nucleotidase, mitochondrial5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase
go.drugbank.com/bio_entities/BE0001620TargetThermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)Catalyzes the transfer of a methyl group from 5-methyltetrahydrofolate to homocysteine resulting in methionine formation.
Polypeptides: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferaseFunction: 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activityOrotidine 5'-phosphate decarboxylase
go.drugbank.com/bio_entities/BE0001677TargetEnzymeEscherichia coli (strain K12)Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
Polypeptides: Orotidine 5'-phosphate decarboxylaseOrotidine 5'-phosphate decarboxylase
go.drugbank.com/bio_entities/BE0001956TargetBacillus subtilis (strain 168)Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).
Polypeptides: Orotidine 5'-phosphate decarboxylaseFunction: orotidine-5'-phosphate decarboxylase activityInosine-5'-monophosphate dehydrogenase
go.drugbank.com/bio_entities/BE0002047TargetStreptococcus pyogenesCatalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays
Polypeptides: Inosine-5'-monophosphate dehydrogenase