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Brensocatib
go.drugbank.com/drugs/DB15638Approved[A274348,A274343] It reduces exacerbations and slows lung function decline, offering a targeted approach to managing NCFB.
Polydatin
go.drugbank.com/drugs/DB11263ApprovedIt is shown to mediate a cytotoxic action on colorectal cancer cells by inducing cell arrest and apoptosis [A27229].
Synonyms: resveratrol-3-O-b-mono-D-glucoside, Resveratrol 3-O-beta-glucopyranosideHydrogenated soybean oil
go.drugbank.com/drugs/DB11302ApprovedAccording to the FDA, hydrogenated soybean oil is generally recognized as safe (GRAS) food substance.
Mitoquinone
go.drugbank.com/drugs/DB05063InvestigationalMitochondrial dysfunction also has been shown to represent an early critical event in the pathogenesis of the sporadic form of Parkinson's disease. … technology, targeted lipophilic cations, that transport and concentrate antioxidants into the mitochondria -- organelles inside cells that provide energy for life processes -- where they accumulate up to
Metiamide
go.drugbank.com/drugs/DB08805ExperimentalIt was an intermediate product on the path to developing cimetidine.
Atuliflapon
go.drugbank.com/drugs/DB19029InvestigationalAtuliflapon is under investigation in clinical trial NCT05251259 (Study to Assess the Efficacy and Safety of Atuliflapon in Moderate-to-severe Uncontrolled Asthma).
Pirlimycin
go.drugbank.com/drugs/DB11537ExperimentalVet approvedPirlimycin hydrochloride is an antibiotic belonging to the _lincosamide_ class. Often marketed as _Pirsue_, this drug is used to treat mastitis in cattle.
BMS-817399
go.drugbank.com/drugs/DB14941InvestigationalBMS-817399 is under investigation in clinical trial NCT01404585 (Proof-of-Concept Study With BMS-817399 to Treat Moderate to Severe Rheumatoid Arthritis).
Ropeginterferon alfa-2b
go.drugbank.com/drugs/DB15119ApprovedInvestigational[A242000, A242005] [Interferon alfa-2b] has been used for decades to treat PV but requires frequent dosing and is not tolerated by all patients.
R411
go.drugbank.com/drugs/DB05468ExperimentalIt is a dual-acting competitive integrin antagonist (as compared to previously developed single integrin antagonists or SIAs) that prevents binding of V-CAM1 to either a4b1 or a4b7.