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Quetiapine
go.drugbank.com/drugs/DB01224ApprovedInvestigationalInitially approved by the FDA in 1997, quetiapine is a second-generation atypical antipsychotic used in schizophrenia, major depression, and bipolar disorder. … It is well-tolerated and a suitable option for some patients with high sensitivity to other drugs, such as [clozapine] and [olanzapine].[A2189]
Categories: Diazepines, Oxazepines, Thiazepines and OxepinesProducts: SEROQUEL 25MG, QUENTIAX 25MGMaprotiline
go.drugbank.com/drugs/DB00934ApprovedIt differs from TCAs in that it does not appear to block serotonin reuptake. … Maprotiline may be used to treat depressive affective disorders, including dysthymic disorder (depressive neurosis) and major depressive disorder.
Categories: Tricyclics and Other Norepinephrine-reuptake InhibitorsProducts: Ludiomil Tab 25mg, Ludiomil Tab 10mgClozapine
go.drugbank.com/drugs/DB00363ApprovedInvestigationalDespite its effectiveness in treating both positive and negative symptoms of schizophrenia, clozapine was briefly removed from the market in various jurisdictions in 1970 due to severe agranulocytosis. … [A185747] However, its promiscuity toward the muscarinic and adrenergic receptors can result in other side effects, notably gastrointestinal hypomotility and orthostatic hypotension. [L905,A215552].
Categories: Diazepines, Oxazepines, Thiazepines and OxepinesProducts: LEPONEX 25MG, CLOZAPIN BETA 25MGDimenhydrinate
go.drugbank.com/drugs/DB00985ApprovedInvestigational[L32980,L32985,L32995] Dimenhydrinate is a combination of [Diphenhydramine] and [8-chlorotheophylline] in a salt form, with 53%-55.5% dried diphenhydramine, and 44%-47% died 8-chlorotheophylline. … [A33889] When used in large doses, dimenhydrinate has been shown to cause a "high" characterized by hallucinations, excitement, incoordination, and disorientation.
Products: Gravol Tab 25mg, DIMERINE SYRUP 25MG/5MLOmalizumab
go.drugbank.com/drugs/DB00043ApprovedInvestigationalBy binding to IgE and neutralizing it, omalizumab reduces free IgE levels and prevents IgE from binding to its receptors on immune cells. … [A39518] Omalizumab was first approved in the US in 2003 [A263507] and in Europe in 2005.
Categories: Amino Acids, Peptides, and ProteinsProducts: Xolair 150mg Powder and Solvent for Solution for Injection, XOLAIR 150MG POWDER AND SOLVENT FOR SOLUTION FOR INJECTIONPlantago seed
go.drugbank.com/drugs/DB11097ApprovedInvestigationalPlatango seeds refer to the seeds collected from various species of plantago trees. It is found in some laxatives for treating occasional constipation and restoring regularity in bowel movements.
Categories: Herbs and Natural ProductsProducts: Up and Up Fiber Therapy, up and up fiber therapy Natural FiberLorazepam
go.drugbank.com/drugs/DB00186ApprovedInvestigational[A957] It was developed by DJ Richards, presented and marketed initially by Wyeth Pharmaceuticals in the USA in 1977. … Lorazepam is a short-acting and rapidly cleared benzodiazepine used commonly as a sedative and anxiolytic.
Categories: Hypnotics and Sedatives, Benzodiazepine hypnotics and sedativesProducts: Ativan Tab 2mg, Nu-loraz Tab 2mgEzetimibe
go.drugbank.com/drugs/DB00973ApprovedInvestigational[A15202] By interfering with the intestinal uptake of cholesterol and phytosterols, ezetimibe reduces the delivery of intestinal cholesterol to the liver.[L11347] … that NPC1L1 plays an essential role in promoting intestinal cholesterol uptake via an ezetimibe-sensitive pathway.
Mixtures: ATOZET TABLET 10MG/20MG, Atozet 10mg/20mg film-coated tabletsCategories: pravastatin and ezetimibe, simvastatin and ezetimibeTrolamine salicylate
go.drugbank.com/drugs/DB11079ApprovedTrolamine salicylate is an organic compound or a salt formed between triethanolamine and salicylic acid. Triethanolamine neutralizes the acidity of the salicylic acid. … Trolamine salicylate serves as an active ingredient in topical over-the-counter products for temporary management of mild to moderate muscular and joint pains.
Products: Up and Up Pain Relief Odorless, Up and Up Odor-free Pain Relieving CreamCladribine
go.drugbank.com/drugs/DB00242ApprovedInvestigationalCladribine is a purine analogue or a chlorinated derivative of adenine [A263733] that causes apoptosis of B and T lymphocytes. … [A263733] In 2017 in Europe and in 2019 in the United States, cladribine was also approved for the treatment multiple sclerosis.[A263718]
Categories: Antineoplastic and Immunomodulating Agents, Nucleic Acids, Nucleotides, and NucleosidesProducts: Mavenclad 10mg Tablets, MAVENCLAD TABLET 10MG