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Displaying results 3791 - 3800 of 10000 in total
  1. Drug

    Mucopolysaccharide polysulphate

    go.drugbank.com/drugs/DB16564
    Investigational

    Products: HIRUDOID GEL 300 mg/100 g, HIRUDOID CREAM 0.3 g/100 g
  2. Target

    Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1

    go.drugbank.com/bio_entities/BE0000087
    TargetHumans

    Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils (By similarity). Forms hydroxylysine r...

    Polypeptides: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
  3. Target

    Gamma-aminobutyric acid receptor subunit alpha-5

    go.drugbank.com/bio_entities/BE0000471
    TargetHumans

    Extrasynaptic alpha-5-containing GABAARs in CA1 pyramidal neurons play a role in learning and memory processes (By similarity) … GABAARs containing alpha-5/GABRA5 subunits are mainly extrasynaptic and contribute to the tonic GABAergic inhibition in the hippocampus (By similarity).

    Polypeptides: Gamma-aminobutyric acid receptor subunit alpha-5Synonyms: GABAAR subunit alpha-5, GABA(A) receptor subunit alpha-5
  4. Target

    1-deoxy-D-xylulose 5-phosphate reductoisomerase

    go.drugbank.com/bio_entities/BE0001575
    TargetEscherichia coli (strain K12)

    Catalyzes the NADPH-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).

    Polypeptides: 1-deoxy-D-xylulose 5-phosphate reductoisomeraseSynonyms: 1-deoxyxylulose-5-phosphate reductoisomerase
  5. Target

    Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

    go.drugbank.com/bio_entities/BE0002192
    TargetHumans

    Forms hydroxylysine residues in -Xaa-Lys-Gly- sequences in collagens. These hydroxylysines serve as sites of attachment for carbohydrate units and are essential for the stability of the intermolecular collagen cross-links

    Polypeptides: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
  6. Target

    T cell receptor beta variable 6-5

    go.drugbank.com/bio_entities/BE0021562
    TargetHumans

    V region of the variable domain of T cell receptor (TR) beta chain that participates in the antigen recognition (PubMed:24600447). Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and ...

    Polypeptides: T cell receptor beta variable 6-5
  7. Drug

    Pirenoxine

    go.drugbank.com/drugs/DB15945
    Investigational

    Categories: Heterocyclic Compounds, 1-RingProducts: KARY UNI OPHTHALMIC SUSPENSION 0.05 mg/ml
  8. Drug

    Clobetasol propionate

    go.drugbank.com/drugs/DB01013
    ApprovedInvestigational

    [A190936] Clobetasol Propionate was granted FDA approval on 27 December 1985.[L11809] … Clobetasol propionate is a prednisolone derivative with higher specificity for glucocorticoid receptors than mineralocorticoid receptors.

    Synonyms: 21-chloro-9-fluoro-11β,17-dihydroxy-16β-methylpregna-1,4-diene-3,20-dione 17-propionate, Clobetasol propionate EInternational brands: Embeline E
  9. Drug

    Aclidinium

    go.drugbank.com/drugs/DB08897
    Approved

    It has a much higher propensity to bind to muscarinic receptors than nicotinic receptors. FDA approved on July 24, 2012.

    Mixtures: Duaklir Genuair 340/12 mcg Inhalation Powder, DUAKLIR®GENUAIR®340/12MCG/DOSIS.Products: EKLIRA®GENUAIR® 322 MCG/DOSIS, Eklira Genuair 322 mcg Inhalation Powder
  10. Drug

    Xanomeline

    go.drugbank.com/drugs/DB15357
    ApprovedInvestigational

    discovered that M1 and M4 muscarinic acetylcholine receptors are highly expressed in brain regions that are implicated in cognition. … Schizophrenia is a complex disease involving a number of different neurotransmitters, including serotonin, dopamine, and acetylcholine.

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 Substrates